An EHR intervention guided by an HIV risk prediction model significantly boosted the uptake of PrEP care among patients of primary care providers (PCPs) who also treat individuals with HIV, according to a study published in JAIDS. Jonathan Volk, MD, and colleagues evaluated the effectiveness of an EHR-based, HIV risk prediction model-guided clinical decision support intervention in improving PrEP provision in primary care. PCPs were randomly assigned to usual care or intervention groups, ensuring a balance care for individuals with HIV between the two arms. PCPs in the intervention group received EHR-based messages prompting discussions on HIV prevention and PrEP before visits with patients whose predicted 3-year HIV risk exceeded a specified threshold. The intervention arm showed a non-significant increase in PrEP care initiation (6.0% vs. 4.5%). There was a significant interaction based on HIV provider status, with an intervention HR of 2.59 (95% CI, 1.30-5.16) for HIV providers and 0.89 (95% CI, 0.59-1.35) for non-HIV providers.
