Photo Credit: ablokhin
The following is a summary of “Epidemiology and Management of Moderate to Severe Thyroid Eye Disease in the United States: Analysis of a Healthcare Claims Database,” published in the December 2024 issue of Endocrinology by Stan et al.
Thyroid eye disease (TED) significantly affects people’s QoL, with moderate to severe cases requiring comprehensive management.
Researchers conducted a retrospective study to estimate the incidence, prevalence, and healthcare utilization of moderate to severe TED in the United States.
They analyzed medical and prescription claims data from the Inovalon deidentified claims database to identify people with moderate to severe TED based on International Classification of Diseases (ICD) codes.
The results showed 3,364 and 1,730 people using sensitive and specific definitions, respectively. Moderate to severe TED incidence was 8.97 (13.49 in women and 4.27 in men) and 4.37 (6.59 in women and 2.05 in men) per 100,000 person-years for sensitive and specific definitions, respectively. The prevalence of moderate to severe TED was 44.13 (66.00 in women and 21.39 in men) and 20.55 (31.18 in women and 9.50 in men) per 100,000 people for sensitive and specific definitions, respectively. Comorbidities such as hypertension were common in over 40% of prevalent cases, and steroids were the most frequently prescribed medication.
They concluded that the substantial burden of moderate to severe TED highlighted the need for a specific ICD code for effective healthcare planning and management.