Hand eczema in glove-wearing patients.

Jun 19, 2023

Experts: Aude Clément,Marie-Christine Ferrier le Bouëdec,Marie-Noëlle Crépy,Nadia Raison-Peyron,Florence Tétart,Pierre Marcant,Pauline Pralong,Aude Valois,Justine Pasteur,Haudrey Assier,Claire Bernier,Marie-Thérèse Le Cam,Florence Hacard,Audrey Nosbaum,Françoise Giordano Labadie,Cécile Morice,Camille Leleu,Brigitte Milpied,Anne-Sophie Darrigade,Juliette Delaunay,Annick Barbaud,Florence Castelain,Evelyne Collet,Emmanuelle Amsler,

Allergic contact dermatitis to gloves is mostly induced by rubber accelerators. The European baseline series (EBS) appears insufficient to detect glove allergy. Since 2017, it is recommended to use the European rubber series (ERS) and to test the patients’ own gloves.
To investigate the clinical profile of glove-wearing patients with hand eczema (HE) and to evaluate their sensitisation profile to glove allergens and the value of testing the patients’ own gloves.
We conducted a French multicentre study of patients evaluated for HE between 2018 and 2020 and tested with the EBS, the ERS and their own gloves in patch tests and semi-open (SO) tests.
A total of 279 patients were included; 32.6% of patients had positive tests to their own gloves or to glove allergens. Almost 45% of the sensitisations to glove allergens were detected only by the ERS. Among the patients tested both in patch tests and SO tests with their own gloves with positive results, 28% had positive SO tests only. Polyvinylchloride (PVC) gloves were positive in four patients.
Our series confirms the need to test the ERS. All the patients’ gloves must also be tested including PVC gloves. SO tests with gloves are useful as a complement to patch tests.

© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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ABOUT THE EXPERTS

Aude Clément,Marie-Christine Ferrier le Bouëdec,Marie-Noëlle Crépy,Nadia Raison-Peyron,Florence Tétart,Pierre Marcant,Pauline Pralong,Aude Valois,Justine Pasteur,Haudrey Assier,Claire Bernier,Marie-Thérèse Le Cam,Florence Hacard,Audrey Nosbaum,Françoise Giordano Labadie,Cécile Morice,Camille Leleu,Brigitte Milpied,Anne-Sophie Darrigade,Juliette Delaunay,Annick Barbaud,Florence Castelain,Evelyne Collet,Emmanuelle Amsler,

Aude Clément

Department of Dermatology, Hôpital Estaing, CHU Clermont-Ferrand, Clermont-Ferrand, France.

Marie-Christine Ferrier le Bouëdec

Department of Dermatology, Hôpital Estaing, CHU Clermont-Ferrand, Clermont-Ferrand, France.

Marie-Noëlle Crépy

Department of Dermatology, Hôpital Cochin Port-Royal, APHP, Paris, France.

Nadia Raison-Peyron

Department of Dermatology, Hôpital Saint Eloi, CHU Montpellier, Montpellier, France.

Florence Tétart

Department of Allergology, Centre Erik Satie, CHU Rouen, Rouen, France.

Pierre Marcant

Department of Dermatology, Hôpital Claude Huriez, CHU Lille, Lille, France.

Pauline Pralong

Department of Dermatology, Hôpital Nord, CHU Grenoble, La Tronche, France.

Aude Valois

Department of Dermatology, Hôpital d’instruction des armées Sainte Anne, Toulon, France.

Justine Pasteur

Department of Dermatology, Hôpital Estaing, CHU Clermont-Ferrand, Clermont-Ferrand, France.

Haudrey Assier

Department of Dermatology, CHU Henri Mondor, Créteil, France.

Claire Bernier

Department of Dermatology, Hôpital Hotel Dieu, CHU Nantes, Nantes, France.

Marie-Thérèse Le Cam

Department of Professional Pathology, Centre hospitalier intercommunal, Créteil, France.

Florence Hacard

Department of Allergology and Immunology, CHU Lyon sud, Lyon, France.

Audrey Nosbaum

Department of Allergology and Immunology, CHU Lyon sud, Lyon, France.

Françoise Giordano Labadie

Department of Dermatology, Hôpital Larrey, CHU Toulouse, Toulouse, France.

Cécile Morice

Department of Dermatology, CHU Caen, Caen, France.

Camille Leleu

Department of Dermatology, CHU Dijon-Bourgogne, Dijon, France.

Brigitte Milpied

Department of Dermatology, Hôpital Saint-André, CHU Bordeaux, Bordeaux, France.

Anne-Sophie Darrigade

Department of Dermatology, Hôpital Saint-André, CHU Bordeaux, Bordeaux, France.

Juliette Delaunay

Department of Dermatology, CHU Angers, Angers, France.

Annick Barbaud

Département de dermatologie et allergologie, Sorbonne Université, INSERM, Institut Pierre Louis d’Epidémiologie et de Santé Publique, AP-HP.Sorbonne Université, Hôpital Tenon, Paris, France.

Florence Castelain

Department of Dermatology, Hôpital Jean Minjoz, CHU Besançon, Besançon, France.

Evelyne Collet

Department of Dermatology, CHU Dijon-Bourgogne, Dijon, France.

Emmanuelle Amsler

Département de dermatologie et allergologie, Sorbonne Université, INSERM, Institut Pierre Louis d’Epidémiologie et de Santé Publique, AP-HP.Sorbonne Université, Hôpital Tenon, Paris, France.