Polycystic ovarian syndrome (PCOS) is a common lifestyle disorder that has become a major international public health concern affecting young women of reproductive age. Homeopathy aims to provide an individual with optimal health on all levels-emotional, mental, physical and spiritual. Homeopathy’s goal is to promote an individual’s overall well-being rather than just treat symptoms. Dr. Boenninghausen’s unique contribution to the promotion of scientific prescribing in homeopathic practice is the concept of remedy relationship and its reportorial analysis. Homeopathy takes into account a person’s natural environment and lifestyle. Then, a homeopathic physician provides treatment that closely matches individual symptoms and recommends homeopathy remedies for the same. A 22-year-old female came into the homeopathic outpatient department (OPD) with complaints of irregular menses, pustular acne and constipation. An ultrasound of the abdomen and pelvis was done to confirm the diagnosis of POCS. Other investigations were performed, including thyroid function tests and hormonal assays, to rule out the presence of other disorders. The case was managed with homeopathic medicines, which were prescribed per Hahnemannian guidelines after referring relationship of remedies.