The following is a summary of “Improving Accuracy of In-The-Bag Intraocular Lens Power Calculation in Adult Eyes with Unilateral Subluxated Lenses by Using the Anterior Chamber Depth of the Unaffected Eye,” published in the March 2024 issue of Ophthalmology by Lou et al.
Anterior chamber depth (ACD) measures space before the eye’s iris. It is crucial for assessing eye health and determining intraocular lens (IOL) power in cataract surgery.
Researchers conducted a prospective study comparing different methods of calculating lens power and refractive outcomes, using either the affected eye’s ACD or the healthy fellow eye’s ACD.
They studied 202 cataractous eyes to compare lens power calculations with and without using the fellow eye’s ACD with the Kane formula. Additionally, they looked at 33 eyes with lens subluxation and compared refractive outcomes using different calculation formulas (the Kane, Barrett Universal II [BUII]m, and Pearl-DGS formulas). The SD of prediction error (PE) was also assessed using the heteroscedastic method.
The results showed no marked ACD was found bilaterally in all patients with cataracts. Using the healthy eye’s ACD for calculations gave comparable results to the affected eye’s ACD (P=0.90, the mean difference [MD] of 0.03±0.03 D). With the affected eye AL, keratometry, and ACD, the median absolute error (MedAE) was 0.38-0.64 D, and the percentage of PE within ±0.50D was 30.30-57.58%. The unaffected eye’s ACD improved the results (MedAE, 0.35-0.49 D; the percentage of PE within ±0.50D, 54.55-63.64%). The newer formulas generally performed better (BUII: 0.82 D, and Pearl-DGS formulas: 0.87D) when using the healthy eye’s ACD, with fewer errors in predicting postoperative outcomes.
Investigators concluded that using healthy eye ACD can improve the accuracy of newer calculation methods, especially for patients with one eye affected by lens subluxation.
Source: karger.com/ore/article/67/1/248/897923/Improving-Accuracy-of-In-The-Bag-Intraocular-Lens