Here are what the editors at HealthDay consider to be the most important developments in Pathology for July 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
High-Sensitivity Blood Test May Help Rule Out Intracranial Injury
TUESDAY, July 31, 2018 (HealthDay News) — A combined test of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) assay results has high sensitivity for detection of intracranial injury among patients with traumatic brain injury (TBI), according to a study published online July 24 in The Lancet Neurology.
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Few Published Programs Address Medical Trainee Mistreatment
TUESDAY, July 31, 2018 (HealthDay News) — There are very few published descriptions of programs that address the mistreatment of medical trainees, according to a review published online July 27 in JAMA Network Open.
Medical Boards May Contribute to Mental Health Stigma for Doctors
MONDAY, July 30, 2018 (HealthDay News) — Existing policy has been amended to encourage licensing boards to require disclosure of physical or mental health conditions only when these would negatively impact a physicians’ ability to practice medicine, according to an article published in the American Medical Association’s AMA Wire.
Four Strategies Help Doctors Make Personal, Professional Gains
MONDAY, July 30, 2018 (HealthDay News) — In an article published in Physicians Practice, four strategies are presented to help physicians make personal and professional gains.
Increased Levels of Human Herpesvirus ID’d in Alzheimer’s
MONDAY, July 30, 2018 (HealthDay News) — Subjects with Alzheimer’s disease have increased levels of two strains of human herpesvirus, according to a study published online July 11 in Neuron.
No Higher Risk of Autoimmune Disorders After HPV4 Vaccination
MONDAY, July 30, 2018 (HealthDay News) — Following quadrivalent human papillomavirus (HPV4) vaccination, girls age 12 to 17 years do not have increased risk of autoimmune disorders, according to a study published recently in CMAJ, the journal of the Canadian Medical Association.
Aldehydes Dominant Carcinogen in Tobacco Smoke
FRIDAY, July 27, 2018 (HealthDay News) — Aldehydes are the major carcinogens in tobacco smoke, according to a study published online June 18 in the Proceedings of the National Academy of Sciences.
2002 to 2014 Saw Hike in AMI Rate in Pregnancy, Puerperium
FRIDAY, July 27, 2018 (HealthDay News) — Acute myocardial infarction (AMI) occurred in one of every 12,400 hospitalizations for those hospitalized during pregnancy and the puerperium, according to a study published online July 18 in the Mayo Clinic Proceedings.
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Assessing, Improving Patient Satisfaction Cuts Malpractice Risk
THURSDAY, July 26, 2018 (HealthDay News) — Assessing and improving patient satisfaction can help physicians avoid being sued for malpractice, according to an article published in Physicians Practice.
Late-Life Blood Pressure Tied to Higher Number of Brain Infarcts
THURSDAY, July 26, 2018 (HealthDay News) — Higher average late-life blood pressure (BP) is associated with an increased number of brain infarcts, according to a study published online July 11 in Neurology.
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Insurers May Be Underpaying Doctors
THURSDAY, July 26, 2018 (HealthDay News) — Insurance companies sometimes underpay doctors the contracted amount for a service or procedure, according to an article published in Medical Economics.
WHO: Congo Ebola Outbreak Over
WEDNESDAY, July 25, 2018 (HealthDay News) — The latest Ebola outbreak in the Democratic Republic of Congo is over, according to the World Health Organization.
First IVF Baby Louise Brown Turns 40
WEDNESDAY, July 25, 2018 (HealthDay News) — It’s been 40 years since the birth of the first baby conceived through in vitro fertilization (IVF), and there have been more than eight million born since.
Tools, Methods of RCTs Can Be Adapted to Real-World Settings
WEDNESDAY, July 25, 2018 (HealthDay News) — Use of appropriate statistical methodology can allow for the synthesis of data collected as part of traditional clinical trials with real-world data, according to an Ideas and Opinions piece published online July 24 in the Annals of Internal Medicine.
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11 Infant Deaths Halt Trial of Sildenafil in Pregnant Women
TUESDAY, July 24, 2018 (HealthDay News) — There have been 11 lung-related infant deaths after pregnant women in the Netherlands were given sildenafil (Viagra) to boost the growth of their babies while in the womb.
VA MISSION Act May Up Costs, Lower Vet Health Care Quality
TUESDAY, July 24, 2018 (HealthDay News) — The Veterans Affairs Maintaining Internal Systems and Strengthening Integrated Outside Networks (VA MISSION) Act may increase costs and reduce quality of health care for veterans, according to an Ideas and Opinions piece published online July 24 in the Annals of Internal Medicine.
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Medical Organizations Must Address Sexual Harassment
MONDAY, July 23, 2018 (HealthDay News) — Medical institutions and organizations need to ensure there are proactive interventions to transform the workplace in order to address sexual harassment and discrimination, according to an article published in the American Medical Association’s AMA Wire.
FDA Warns Against Risks of Contaminated Synthetic Cannabis
MONDAY, July 23, 2018 (HealthDay News) — Users of synthetic marijuana products and health care providers should be aware of the risk of bleeding associated with contamination of synthetic cannabinoid products with brodifacoum, according to the U.S. Food and Drug Administration.
Increased Coverage in States With Medicaid Expansion
FRIDAY, July 20, 2018 (HealthDay News) — Coverage rates and access to care are significantly higher in states with Medicaid expansion, compared with non-expansion states, according to a study published in the July issue of Health Affairs.
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Molecular Autopsy May Shed Light on Sudden Death in Young
FRIDAY, July 20, 2018 (HealthDay News) — Ultrarare, nonsynonymous variants are seen in 64 percent of victims of sudden unexplained death in the young (SUDY), with 10 of the 27 variants considered pathogenic or likely pathogenic, according to a study published in the June 19 issue of Circulation.
WTC-Related PTSD May Up Risk for Stroke, MI in Clean-Up Crew
THURSDAY, July 19, 2018 (HealthDay News) — World Trade Center-related post-traumatic stress disorder (PTSD) is a risk factor for myocardial infarction (MI) and stroke among workers involved in cleaning up the debris, according to a study published in the June issue of Circulation: Cardiovascular Quality and Outcomes.
Link for Asbestos-Free Talcum Powder, Cancer Not Clear
THURSDAY, July 19, 2018 (HealthDay News) — Talcum powder, made from talc, which contains asbestos is considered carcinogenic to humans, while the carcinogenicity of talc without asbestos is unclear, according to the American Cancer Society.
Overall Cancer Mortality Rates Decreasing for Men and Women
WEDNESDAY, July 18, 2018 (HealthDay News) — Cancer incidence rates have decreased among men but remained stable among women, while cancer death rates are decreasing for both men and women, according to a report published in the July 1 issue of Cancer.
Australian Researchers Develop First Blood Test for Melanoma
WEDNESDAY, July 18, 2018 (HealthDay News) — The first blood test to detect melanoma skin cancer in its early stages has been created, according to a study published in the July 17 issue of Oncotarget.
Seven Strategies Can Help Practices Manage Staff Time Off
WEDNESDAY, July 18, 2018 (HealthDay News) — Several strategies can be implemented to help address management of staff time off, allowing mutual respect for the employee and employer requests, according to an article published in Medical Economics.
Risk of CRC, Non-CRC Death Up With Positive Fecal Hb Test
WEDNESDAY, July 18, 2018 (HealthDay News) — Individuals with a positive fecal hemoglobin (f-Hb) test result have an increased risk of dying from colorectal cancer (CRC) and non-CRC causes, according to a study published online July 16 in Gut.
Alternative Payment Models Should Include Precision Medicine
TUESDAY, July 17, 2018 (HealthDay News) — The American Medical Association has committed to working to integrate precision medicine into alternative payment models (APMs), according to an article published in the association’s AMA Wire.
Trials Supporting FDA Approval of Breakthrough Drugs Examined
TUESDAY, July 17, 2018 (HealthDay News) — Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a research letter published in the July 17 issue of the Journal of the American Medical Association.
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Shared Decision-Making Approach to Zika Best for Travelers
TUESDAY, July 17, 2018 (HealthDay News) — An approach to shared decision-making that stratifies risk might be most appropriate for preventing Zika infection, according to an Ideas and Opinion piece published online July 17 in the Annals of Internal Medicine.
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FDA Establishes New Task Force on Drug Shortages
TUESDAY, July 17, 2018 (HealthDay News) — In a recent statement, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., announced the formation of a new drug shortages task force to thoroughly explore the reasons why drug shortages remain a persistent challenge.
FDA Approves First Drug to Treat Smallpox
MONDAY, July 16, 2018 (HealthDay News) — TPOXX (tecovirimat) has been approved by the U.S. Food and Drug Administration to treat smallpox.
Adoption of EHR Linked to Reduction in Mortality Rates
MONDAY, July 16, 2018 (HealthDay News) — Adoption of electronic health records (EHRs) is associated with a reduction in mortality rates in U.S. hospitals, according to a study published in the July issue of Health Affairs.
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Physician Burnout Tied to Higher Risk of Medical Errors
MONDAY, July 16, 2018 (HealthDay News) — Physician burnout, fatigue, and work-unit safety grades are independently associated with medical errors, according to a study published online July 9 in the Mayo Clinic Proceedings.
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Jury Awards $4.62B in Johnson & Johnson Talcum Powder Lawsuit
FRIDAY, July 13, 2018 (HealthDay News) — A jury says Johnson & Johnson must pay $4.62 billion to 22 women who allege they developed ovarian cancer after using the company’s Baby Powder and Shower to Shower brand talcum powder as part of their daily feminine hygiene routine.
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Virtual Assistants Not HIPAA Compliant
FRIDAY, July 13, 2018 (HealthDay News) — Virtual assistant programs like Google Assistant, Siri, and Alexa are not yet in compliance with the Health Insurance Portability and Accountability Act (HIPAA), warns an article published in Medical Economics.
Two Regimens Fail to Stop Declines in β-Cell Function
FRIDAY, July 13, 2018 (HealthDay News) — Neither glargine followed by metformin nor metformin alone halts the progressive deterioration of β-cell function in youth with impaired glucose tolerance (IGT) or recently-diagnosed type 2 diabetes, according to a study published online June 25 in Diabetes Care.
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Gender Bias in Medicine Has Far-Reaching Consequences
FRIDAY, July 13, 2018 (HealthDay News) — Overlooking women in medicine can have far-reaching consequences, according to a perspective piece published in the June 14 issue of the New England Journal of Medicine.
AMA Aims to Boost Affordability of ACA Marketplace Plans
THURSDAY, July 12, 2018 (HealthDay News) — The American Medical Association (AMA) House of Delegates has adopted policy to increase the number of people who obtain coverage through the Affordable Care Act (ACA) by making marketplace plans more affordable.
2001 to 2015 Saw Decline in Self-Employment in Health Care
THURSDAY, July 12, 2018 (HealthDay News) — From 2001 to 2015 there was a decrease in the percentage of health care professionals who are self-employed and a decrease in the earning gap between self-employed and employed health care professionals, according to a study published online July 12 in JAMA Network Open.
Mosaic HIV-1 Vaccine Induces Responses in Humans, Monkeys
THURSDAY, July 12, 2018 (HealthDay News) — A mosaic adenovirus serotype 26 (Ad26)-based HIV-1 vaccine induces immune responses in humans and rhesus monkeys, according to a study published online July 6 in The Lancet.
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Peer-Led Education Helps Physicians Save Time With EHRs
THURSDAY, July 12, 2018 (HealthDay News) — A peer-based education program can improve the efficiency of electronic health record (EHR) use, according to an article published in the American Medical Association’s AMA Wire.
Universal Screening Best Strategy for Hepatitis C in France
WEDNESDAY, July 11, 2018 (HealthDay News) — Universal screening is the most effective strategy for hepatitis C virus (HCV) in France, according to a study published online July 1 in the Journal of Hepatology.
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Attending Surgeon Influences Genetic Testing in Breast Cancer
WEDNESDAY, July 11, 2018 (HealthDay News) — The attending surgeon is associated with variation in the receipt of genetic testing after breast cancer diagnosis, according to a study published online July 3 in JAMA Surgery.
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Advanced Prostate Cancer Variant More Common Than Thought
WEDNESDAY, July 11, 2018 (HealthDay News) — The incidence of treatment-emergent small-cell neuroendocrine prostate cancer (t-SCNC) is 17 percent among patients with metastatic castration-resistant prostate cancer (mCRPC), and many t-SCNC biopsy specimens have androgen receptor (AR) amplification and protein expression, according to a study published online July 9 in the Journal of Clinical Oncology.
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AMA Calls for Inclusive Family, Medical Leave Policies
TUESDAY, July 10, 2018 (HealthDay News) — The American Medical Association (AMA) calls for inclusive family and medical leave policies to support lesbian, gay, bisexual, transgender, and queer (LGBTQ) workers who care for relatives, spouses, and partners.
International Group Develops Best Practices for Drug Packaging
TUESDAY, July 10, 2018 (HealthDay News) — Nine new drug labeling and packaging guidelines have been developed with an aim of reducing medication errors, according to a report published in Drug Topics.
Error Rate 7.4 Percent in Speech Recognition-Assisted Notes
TUESDAY, July 10, 2018 (HealthDay News) — The error rate in speech recognition (SR)-assisted documentation is 7.4 percent, according to a study published online July 6 in JAMA Network Open.
Pelvic Exam in ER Doesn’t Help Predict STI for Young Females
TUESDAY, July 10, 2018 (HealthDay News) — Pelvic examination does not increase the sensitivity or specificity for diagnosis of chlamydia, gonorrhea, or trichomonas over taking a history alone for young female patients presenting to the emergency department with suspected cervicitis or pelvic inflammatory disease, according to a study published online July 2 in the Annals of Emergency Medicine.
Patient Interest Fairly High for Melanoma Genetic Risk Testing
TUESDAY, July 10, 2018 (HealthDay News) — There is moderately high interest in genetic testing for melanoma risk among the general population, according to a study published in the June issue of JAMA Dermatology.
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FDA Drops Zika Testing for Blood Donors
MONDAY, July 9, 2018 (HealthDay News) — Individual blood donations will no longer need to be tested for the Zika virus, according to the U.S. Food and Drug Administration.
Mucus Protects Airborne Flu Virus at All Humidities
MONDAY, July 9, 2018 (HealthDay News) — Influenza virus aerosols remain infectious at all humidity levels, according to a study published online June 7 in the Journal of Infectious Diseases.
Sleep Apnea Linked to Changes in the Brain in Older Adults
MONDAY, July 9, 2018 (HealthDay News) — Obstructive sleep apnea (OSA) is associated with changes to the structure of the brain that are seen in the early stages of dementia, according to a study published online July 5 in the European Respiratory Journal.
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Tick-Caused Meat Allergy on the Rise in the United States
FRIDAY, July 6, 2018 (HealthDay News) — Red meat allergy caused by a bite from the lone star tick appears to be on the rise in the United States, a researcher says.
Risk-Stratified Breast Cancer Screening Ups Cost-Effectiveness
FRIDAY, July 6, 2018 (HealthDay News) — Risk-stratified breast screening improves the cost-effectiveness of screening, according to a study published online July 5 in JAMA Oncology.
IT Solutions for Easier EHRs Save Physicians Time, Burnout
FRIDAY, July 6, 2018 (HealthDay News) — Yale Medicine is effectively targeting electronic health record (EHR) use and functionality as a way to improve physician job satisfaction and reduce burnout, according to an article published in the American Medical Association’s AMA Wire.
Organic Solvents + Genetics May Increase Risk of Multiple Sclerosis
FRIDAY, July 6, 2018 (HealthDay News) — The combination of genetics and exposure to organic solvents in paints and varnishes increases the risk of multiple sclerosis (MS), according to a study published online July 3 in Neurology.
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Hospitals Face $218B in Federal Payment Cuts From 2010 to 2028
THURSDAY, July 5, 2018 (HealthDay News) — Cumulative reductions in federal payments to hospitals from 2010 to 2028 are estimated to reach $218.2 billion, according to a study commissioned by the Federation of American Hospitals and the American Hospital Association (AHA).
Patient Complaints Mainly About Rudeness, Rushing, Reproach
THURSDAY, July 5, 2018 (HealthDay News) — Understanding patients’ complaints about practice can be instructive for physicians, according to an article published June 6 in Physicians Practice.
Viruses ID’d As Most Common Cause of Meningitis in U.K. Adults
THURSDAY, July 5, 2018 (HealthDay News) — Viruses are the most commonly identified cause of meningitis among U.K. adults, according to a study published online June 29 in The Lancet Infectious Diseases.
HPV Cervical CA Screening Cuts Odds of Later CIN3+ Diagnosis
TUESDAY, July 3, 2018 (HealthDay News) — The use of primary human papillomavirus (HPV) testing versus cytology results in reduced likelihood of cervical intraepithelial neoplasia (CIN) grade 3 or worse (CIN3+) at 48 months, according to a study published in the July 3 issue of the Journal of the American Medical Association.
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Oral Insulin Choline, Geranate Ionic Liquid Shows Promise
TUESDAY, July 3, 2018 (HealthDay News) — An oral insulin formulation has been developed using choline and geranate (CAGE) ionic liquid, which significantly reduces blood glucose levels in vivo for a sustained period, according to a study published online June 25 in the Proceedings of the National Academy of Sciences.
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Automated Bone Scan Index Prognostic for Prostate Cancer
TUESDAY, July 3, 2018 (HealthDay News) — The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a study published online May 17 in JAMA Oncology.
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