The Wada test is the gold standard for language localization, although it is intrusive and demands a significant amount of human and material resources. Although functional MRI and tractography using diffusion tensor imaging (DTI) have shown to be beneficial for finding language in epilepsy surgery, there is no indication of a link between both the Wada tests and DTI MRI in language dominance.From 2012 to 2017, the researchers looked at individuals who had a Wada test before epilepsy surgery at their institution. The scientists looked examined fractional anisotropy (FA), the quantity and length of fibres, and the volume of the arcuate and uncinate fasciculi in hindsight. The researchers compared dominant and nondominant hemispheres, as well as dominant and nondominant hemipheres.
The medical records of ten patients with temporal lobe epilepsy were examined. The dominant hemisphere’s mean FA of the arcuate fasciculus was higher than the nondominant hemisphere, according to statistical analysis. In the dominant hemisphere, the number of fibres in the arcuated fasciculum was higher (881.5 vs 305.4, p = 0.003). There were no variations in the length of uncinate fascicule fibres. DTI examination of the arcuate fasciculus and other tract bundles could be effective for language location tests in individuals with refractory epilepsy before surgery.
Reference Link – https://thejns.org/view/journals/j-neurosurg/134/6/article-p1703.xml
