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The following is a summary of “Oncologic Outcomes of Laparoscopic Radical Hysterectomy Incorporating Modified Tumor-Free Techniques,” published in the December 2024 issue of Obstetrics and Gynecology by Li et al.    

Modifying laparoscopic radical hysterectomy to adopt tumor-free principles may improve oncologic outcomes in patients with early-stage cervical cancer.  

Researchers conducted a retrospective study to assess modified tumor-free (MTF) laparoscopic radical hysterectomy to improve oncologic outcomes in patients with early-stage cervical cancer.  

They involved 276 patients with early-stage cervical cancer, 151 in the MTF group, and 125 in the non-MTF group treated (January 2017 to January 2023). Oncologic outcomes and perioperative results were analyzed using inverse probability treatment weighting (IPTW).  

The results showed that patients in the MTF group had shorter hospital stays but no differences in operative time decreased hemoglobin, or complications. After a median follow-up of 36.0 months (range 15.3–62.0 months) for the MTF group and 66.8 months (range 3.0–82.5 months) for the non-MTF group, recurrence occurred in 2 (1.3%) patients with MTF and 16 (12.8%) non-MTF. The 2-year disease-free survival (DFS) rates were 99.3% for the MTF group and 91.9% for the non-MTF group. Adjusted multivariate analysis showed that MTF techniques were an independent predictor of longer DFS (HR 0.10, 95% CI, 0.01–0.77, P=.027). After IPTW, patients in the MTF group had more favorable DFS than those in the non-MTF group (log-rank P=.031).  

They concluded that MTF laparoscopic radical hysterectomy was a feasible treatment for patients with early-stage cervical cancer, resulting in better oncologic outcomes than conventional surgery.  

Source: journals.lww.com/greenjournal/fulltext/9900/oncologic_outcomes_of_laparoscopic_radical.1195.aspx