Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for May 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Metformin Recalled Due to Potential Cancer-Causing Chemical

FRIDAY, May 29, 2020 (HealthDay News) — A recall of the widely used diabetes drug metformin was announced by drug maker Apotex due to possible high levels of N-Nitrosodimethylamine (NDMA), which is believed to cause cancer in people.

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Tooth Loss More Prevalent in Adults With Chronic Disease

THURSDAY, May 28, 2020 (HealthDay News) — Adults with severe chronic disease or with fair or poor general health have a higher prevalence of edentulism and severe tooth loss, according to research published in the May 29 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Links Found Between Leaders of Medical Associations, Industry

THURSDAY, May 28, 2020 (HealthDay News) — There are extensive financial relationships between leaders of U.S. professional medical associations and industry, according to a study published online May 27 in The BMJ.

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9.5 Percent Uninsured in U.S. From January Through June 2019

WEDNESDAY, May 27, 2020 (HealthDay News) — A total of 9.5 percent of persons were uninsured from January through June 2019, according to a report published online May 28 by the National Center for Health Statistics.

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Improving Glycemic Control May Also Aid COVID-19 Outcomes

THURSDAY, May 28, 2020 (HealthDay News) — Insulin infusion helps achieve glycemic targets and may reduce the risk for poor outcomes in patients with hyperglycemia and COVID-19, according to a study published online May 19 in Diabetes Care.

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U.K. Patients Hospitalized With COVID-19 Are More Often Male

WEDNESDAY, May 27, 2020 (HealthDay News) — Patients hospitalized with COVID-19 are more often male and frequently have comorbidities, according to a study published online May 22 in the The BMJ.

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Only One in Four U.S. Hospitals With ICUs Have Tele-ICU Services

WEDNESDAY, May 27, 2020 (HealthDay News) — In 2018, half of U.S. hospitals had the capacity to conduct telehealth-based outpatient visits, while only one in four had tele-intensive care unit (tele-ICU) capabilities, according to a research letter published online April 30 in the Annals of Internal Medicine.

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New Medicare Benefit Would Limit Insulin Copays to $35 a Month

TUESDAY, May 26, 2020 (HealthDay News) — Reacting to skyrocketing prices for insulin, the Trump Administration announced on Tuesday a new benefit that would limit Medicare recipients’ copays for insulin to a maximum of $35 a month and save them about $446 a year if they have prescription plans that offer the benefit.

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High Prevalence of Primary Aldosteronism Observed

TUESDAY, May 26, 2020 (HealthDay News) — Primary aldosteronism is prevalent and increases in parallel with hypertension severity, according to a study published online May 26 in the Annals of Internal Medicine.

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Age, Sex, History of Diabetes Predict Intubation in COVID-19

FRIDAY, May 22, 2020 (HealthDay News) — Older age, male sex, and history of diabetes are factors predictive of intubation among hospitalized patients with COVID-19, while age and body mass index are associated with time to extubation, according to a study published online May 19 in Otolaryngology-Head and Neck Surgery.

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Antiobesity Meds May Curb Weight Regain After RYGB

FRIDAY, May 22, 2020 (HealthDay News) — The antiobesity medications (AOMs) phentermine and topiramate may help mitigate weight regain (WR) after Roux-en-Y gastric bypass (RYGB) surgery, according to a study published online May 22 in Obesity.

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Weight in Adolescence Tied to Early-Onset Type 2 Diabetes

FRIDAY, May 22, 2020 (HealthDay News) — Obesity in adolescence significantly increases the risk for incidence of type 2 diabetes in early adulthood in both sexes, according to a study published online April 22 in Diabetes Care.

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Higher Number of Pregnancy Losses Tied to Subsequent Type 2 Diabetes

THURSDAY, May 21, 2020 (HealthDay News) — Pregnancy loss is associated with subsequent type 2 diabetes, with an increased likelihood for increasing number of pregnancy losses, according to a study published online May 19 in Diabetologia.

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Excessive Drinking Seen in Some Patients With Chronic Conditions

WEDNESDAY, May 20, 2020 (HealthDay News) — Among those reporting alcohol use, patients with certain common medical conditions are more likely to report excessive drinking, according to a study published online May 13 in JAMA Network Open.

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Age, CRP Up Risk for Mortality in Diabetes With COVID-19

WEDNESDAY, May 20, 2020 (HealthDay News) — For patients with diabetes and COVID-19, risk factors for mortality include older age and elevated C-reactive protein, and insulin usage is associated with poor prognosis, according to a study published online May 14 in Diabetes Care.

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Spending on Primary Care Continues to Lag in the U.S.

TUESDAY, May 19, 2020 (HealthDay News) — Spending on inpatient services, specialty care, and prescriptions together accounted for about two-thirds of the increase in total U.S. health care spending from 2002 to 2016, according to a research letter published online May 18 in JAMA Internal Medicine.

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Burnout Comparable Between Millennial, Gen X Residents, Fellows

TUESDAY, May 19, 2020 (HealthDay News) — Millennial and Generation X medical residents and fellows experience similar rates of burnout and have similar levels of empathy, according to a study published online May 5 in Academic Psychiatry.

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28 Million-Plus Surgeries Could Be Canceled Due to COVID-19

TUESDAY, May 19, 2020 (HealthDay News) — Worldwide, more than 28 million elective surgeries could be canceled or postponed during the 12 weeks of peak disruption due to COVID-19, according to a study published online May 12 in the British Journal of Surgery.

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Higher Intake of Whole-Fat Dairy May Cut Metabolic Syndrome Risk

TUESDAY, May 19, 2020 (HealthDay News) — Higher intake of whole-fat dairy products is associated with a lower prevalence of metabolic syndrome (MetS) as well as hypertension and diabetes, according to a study published online May 18 in BMJ Open Diabetes Research & Care.

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Osteoporotic Fracture Risk Lower for DOAC Than Warfarin in A-Fib

MONDAY, May 18, 2020 (HealthDay News) — For patients with atrial fibrillation (AF), the risk for osteoporotic fracture appears to be lower with direct oral anticoagulant (DOAC) use compared with warfarin use, according to a study published online May 19 in the Annals of Internal Medicine.

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Guidance Issued for Osteoporosis Management During COVID-19

FRIDAY, May 15, 2020 (HealthDay News) — In a joint guidance document issued by the American Society for Bone and Mineral Research, American Association of Clinical Endocrinologists, Endocrine Society, European Calcified Tissue Society, and National Osteoporosis Foundation, recommendations are presented for the management of osteoporosis during the COVID-19 pandemic.

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Most Physicians Have Seen False-Negative COVID-19 Test Results

MONDAY, May 18, 2020 (HealthDay News) — Most physicians believe they have seen false-negative results for a COVID-19 diagnostic test, according to the results of a recent survey.

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Early Diagnosis of Gestational Diabetes Leads to Less Weight Gain

FRIDAY, May 15, 2020 (HealthDay News) — Early diagnosis and treatment of gestational diabetes mellitus (GDM) in high-risk women improves gestational weight gain (GWG), according to a study published online April 24 in the Journal of Women’s Health.

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T2DM Linked to Worse Cognitive Performance After Stroke

FRIDAY, May 15, 2020 (HealthDay News) — In a stroke population, type 2 diabetes (T2D), but not impaired fasting glucose, is associated with worse cognitive performance, according to a study published online May 14 in Stroke.

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Experts Discuss Strategy for Bariatric Surgery During COVID-19

WEDNESDAY, May 13, 2020 (HealthDay News) — In a personal view article, published online May 7 in The Lancet Diabetes & Endocrinology, recommendations are presented for the management of bariatric and metabolic surgery patients during the COVID-19 pandemic.

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Burden of Osteoarthritis Increasing in Most Countries

WEDNESDAY, May 13, 2020 (HealthDay News) — The burden of osteoarthritis (OA) is increasing in most countries, according to a study published online May 12 in Annals of the Rheumatic Diseases.

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Grip Strength May Help ID Type 2 Diabetes Risk in Healthy Adults

WEDNESDAY, May 13, 2020 (HealthDay News) — Grip strength may predict type 2 diabetes risk in healthy adults, according to a study recently published in the American Journal of Preventive Medicine.

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Thigh Circumference Tied to Hypertension Risk

TUESDAY, May 12, 2020 (HealthDay News) — Large thigh circumference is associated with a lower risk for hypertension in overweight and obese individuals, according to a study published in the April issue of Endocrine Connections.

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Bone Health Declining in U.S. Adults With and Without Prediabetes

TUESDAY, May 12, 2020 (HealthDay News) — The bone health of adults older than 40 years of age is declining for individuals both with normal glucose regulation and prediabetes, according to a study recently published in Diabetes Care.

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Severe Illness Reported in Some Children With COVID-19

TUESDAY, May 12, 2020 (HealthDay News) — Severe illness from COVID-19 infection occurs in some children, most of whom have significant preexisting comorbidities, according to a study published online May 11 in JAMA Pediatrics.

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Link Found Between Body Size in Childhood, Later Life Disease

THURSDAY, May 7, 2020 (HealthDay News) — Large adult body size contributes to the association between genetically predicted larger body size in childhood and coronary artery disease and type 2 diabetes later in life, according to a study published online May 6 in The BMJ.

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Well-Controlled Blood Glucose May Improve COVID-19 Outcomes

WEDNESDAY, May 6, 2020 (HealthDay News) — For patients with COVID-19 and type 2 diabetes (T2D), well-controlled blood glucose (BG) is associated with lower mortality during hospitalization, according to a study published online May 1 in Cell Metabolism.

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L-Thyroxine Does Not Improve Subclinical Hypothyroidism in ≥65s

TUESDAY, May 5, 2020 (HealthDay News) — L-thyroxine does not improve hypothyroid symptoms or tiredness among older adults with subclinical hypothyroidism (SCH) and high symptom burden, according to a study published online May 5 in the Annals of Internal Medicine.

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Sleep Apnea Tied to High Blood Glucose Levels Among Blacks

MONDAY, May 4, 2020 (HealthDay News) — Black Americans with severe sleep apnea are more likely to have high blood glucose levels, according to a study published online April 28 in the Journal of the American Heart Association.

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Testing, Prescribing Increase After Change to TSH Reference Range

MONDAY, May 4, 2020 (HealthDay News) — A minor planned decrease in the upper limit of the reference range for thyroid-stimulating hormone (TSH) resulted in an increase in levothyroxine prescriptions and more TSH measurements, according to a study published in the May 4 issue of CMAJ, the journal of the Canadian Medical Association.

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CV Outcomes Improved in Those With, Without Type 2 Diabetes

FRIDAY, May 1, 2020 (HealthDay News) — Cardiovascular outcomes have improved since the 1990s, especially for individuals with type 2 diabetes, according to a study published online April 30 in the Journal of Clinical Endocrinology & Metabolism.

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Lower Lean Body Mass With Aging May Up Diabetes Incidence in Men

FRIDAY, May 1, 2020 (HealthDay News) — Changes in total lean body mass with aging are associated with the development of diabetes among men and women, according to a study published online April 30 in the Journal of the Endocrine Society.

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SGLT2 Inhibitors Linked to Reduced Risk for Serious Renal Events

FRIDAY, May 1, 2020 (HealthDay News) — Use of sodium-glucose cotransporter 2 (SGLT2) inhibitors is associated with a reduced risk for serious renal events compared with dipeptidyl peptidase-4 inhibitors, according to a study published online April 29 in The BMJ.

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