To carry out a nonsystematic analysis of the microbiota literature on various forms of food allergy not mediated with IgE is the purpose of this study. Eosinophilic oesophagitis, food protein-induced enteropathy, dietary protein-induced enterocolitis syndrome and food protein-induced allergic proctocolitis are among the most serious non-IgE-mediated allergy-managed disorders. The study explains how the researchers detect a rise in proteobacteria at phylum level of eosinophilic esophageal microbiota and enterocolitis syndrome caused by food protein and food protein-induced allergic proctocolitis gut microbiota whereas bacteroidetes increase in healthy controls.

The recent increase in food allergy incidence cannot be attributed solely to genetic causes, and the microbiome may be leading to allergy danger. The study found that common pathological microbiota characteristics can be established in various forms of non-IgE-mediated food allergies. These findings point to a potential function for the microbiota in pathogenesis and non-IgE-mediated food allergies, as well as the importance of understanding the influence of microbiota regulation on the disorders themselves.

Reference: https://journals.lww.com/co-allergy/Abstract/2020/06000/Microbiota_in_non_IgE_mediated_food_allergy.18.aspx

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