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The following is a summary of “Multi-omics in Allergic Rhinitis: Mechanism Dissection and Precision Medicine,” published in the February 2025 issue of Clinical Reviews in Allergy & Immunology by Hao et al.
Allergic rhinitis (AR) is a chronic airway disease caused by inhaled allergens, with rising prevalence. It affects quality of life, induces comorbidities, and burdens society.
Researchers conducted a retrospective study on the limitations of current diagnostic and treatment methods for AR. Advanced approaches offer the potential for improved management.
They analyzed differentially expressed DNA, RNA, proteins, and metabolites in patients with AR using multi-omics technology to understand pathogenic mechanisms, identify key molecules, and design personalized treatment.
The results showed progress in using genomics, epigenomics, transcriptomics, proteomics, and metabolomics to study AR. They summarized and analyzed data from previous studies, highlighting the role of multi-omics technology in improving diagnosis and treatment.
Investigators illustrated the role of multi-omics technologies in improving the diagnosis and treatment of AR.
Source: link.springer.com/article/10.1007/s12016-025-09028-3
