The following is a summary of “Incidences of postoperative hypoparathyroidism during thyroid surgery with ipsilateral central lymph node dissection for papillary thyroid carcinoma were close to that during thyroid surgery for benign thyroid diseases necessitating surgical intervention: a retrospective study,” published in the December 2024 issue of Endocrinology by Wang et al.
Postoperative hypoparathyroidism is a common complication after thyroid surgery. The impact of central lymph node dissection (CLND) on the incidence remains uncertain.
Researchers conducted a retrospective study evaluating the effect of CLND on postoperative hypoparathyroidism.
They compared the incidence of postoperative hypoparathyroidism between people undergoing thyroidectomy with central neck dissection (CND) for papillary thyroid carcinoma (PTC) and those receiving thyroidectomy for benign thyroid conditions (follicular adenoma and/or nodular goiter), assessing immediate, protracted, and permanent hypoparathyroidism (immediate: 9.2% vs. 3.0%, P=0.157; protracted: 4.6% vs. 0%, P=0.06; permanent: 0% vs. 0%, P>0.99).
The results showed that the incidence of postoperative hypoparathyroidism was not significantly different between people undergoing lobe thyroidectomy for benign thyroid diseases and people undergoing lobe thyroidectomy with ipsilateral CLND for PTC (immediate: 9.2% vs. 3.0%, P=0.157; protracted: 4.6% vs. 0%, P=0.06; permanent: 0% vs. 0%). No significant difference in the incidence between people undergoing total thyroidectomy for benign thyroid diseases and people undergoing total thyroidectomy with ipsilateral CLND for PTC (immediate: 25.0% vs. 33.8%, P=0.12; protracted: 4.5% vs. 5.3%, P=0.99; permanent: 1.1% vs. 0.9%, P>0.99).
They concluded that the incidence of postoperative hypoparathyroidism in thyroid surgery with CLND was like that in surgery for benign thyroid diseases.
Source: frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1461553/full
