An increase in PrEP prescriptions from 2014 to 2022 in New York City correlated with a decrease in new HIV diagnoses, but racial and ethnic inequalities remained, ac – cording to findings published in AIDS. Benjamin Katz, MPH, MIA, and colleagues compared trends in PrEP with trends in HIV diagnoses. The number of people filling at least one PrEP prescription rose from 2,551 in 2014 to 35,742 in 2022, while over – all HIV diagnoses declined from 48.1 per 100,000 in 2003 to 17.1 per 100,000 in 2022. Following PrEP rollout, faster declines were seen for White men (2014–2019 annual percentage change [APC]: −16.6%), Asian/Pacific Islander men (2016–2022 APC: −9.8%), men aged 20–29 (2017–2020 APC: −9.4%) and 40–49 (2014–2020 APC: −12.2%), Latino/Hispanic people aged 40–49 (2015–2020 APC: −13.0%), White people aged 20–29 (2012– 2022 APC: −11.4%) and 40–49 (2014–2018 APC: −27.8%), and Asian/Pacific Islander people aged 20–29 (2017–2022 APC: −13.0%).