Screening for vitamin D status in celiac disease (CD) has been suggested, although the research is mixed. For this study, researchers wanted to investigate vitamin D status in newly diagnosed children with CD and a non-CD control group, as well as to correlate it with vitamin D consumption. Serum 25-hydroxyvitamin D (25-OHD) levels were measured in children with newly diagnosed CD and compared to pediatric outpatients with functional abdominal symptoms in cross-sectional research. Anthropometric data, as well as vitamin D intake via milk and multivitamin use, were gathered. The study included 38 newly diagnosed CD patients (10.4 ± 3.0 years old; 50% girls) and 82 controls (11.2 ± 4.2 years old; 58.5% girls). Except for average daily D consumption and BMI, both groups were similar. Mean 25-OHD levels did not differ statistically between CD (26.4 ± 8.0 ng/mL) and controls (23.5 ± 8.2 ng/mL) [P≤0.07]. Suboptimal D status was prevalent in both groups (65.8% CD and 79.3% controls). 25-OHD levels were found to be substantially associated with age (r = -0.262; P< 0.0038) and estimated vitamin D consumption (r=0.361; P< 0.0001).
There was no significant difference in 25-OHD levels between newly diagnosed CD and controls, but both had insufficient 25-OHD levels. 25-OHD levels were shown to be significantly related to vitamin D consumption, indicating that patients and controls absorbed the same amount of vitamin D. Because CD is linked to bone illness and D status is typically poor, measures to optimize D, such as screening levels at diagnosis, must be made.
Reference:journals.lww.com/jpgn/Fulltext/2019/10000/Should_We_Assess_Vitamin_D_Status_in_Pediatric.12.aspx
