The Sino-Nasal Outcome Test (SNOT-22) was effective for studying treatment outcomes in nasal obstruction, according to results published in the American Journal of Otolaryngology. Chadi Makary, MD, FACS, and colleagues conducted a prospective cohort study to validate SNOT-22 and determine whether it correlated with the Nasal Obstruction and Septoplasty Effectiveness (NOSE) scale. Patients presenting for nasal obstruction secondary to nasal septal deviation and/ or inferior turbinate hypertrophy (N=126; average age, 42.6) completed both the SNOT-22 and the NOSE questionnaires. SNOT-22 and NOSE scores correlated well preoperatively and postoperatively (both P<0.0001). The rhinologic and sleep SNOT-22 subdomains scores had the strongest correlation to NOSE score (both P<0.0001). Both NOSE and SNOT-22 scores improved postoperatively [NOSE: 67.4 vs 25.1 (P<0.0001) at 3 months and 69.5 vs 34.0 (P<0.0001) at 6 months; SNOT-22: 37.1 vs 25.2 (P=0.002) at 3 months and 38.1 vs 22.6 (P=0.002) at 6 months].