Its overview of an Electrical stimulation of the endopiriform nucleus attenuates epilepsy in rats by network modulation . Persistent epilepsy was actuated by cobalt wire implantation in the engine cortex singularly. Bipolar‐stimulating cathodes were embedded into the EPN respectively. Ceaseless electroencephalography (EEG) was recorded utilizing anodes set into two-sided engine cortex and hippocampus CA1 territories. The endopiriform core (EPN) is a well‐defined core of the rat olfactory framework, which contains an enormous, lengthened convergence of multipolar neurons found profound to the piriform cortex (PC) over its full rostral to caudal degree. There are thick plexus of characteristic associations inside the EPN and thick equal associations between the EPN and the overlying PC. Unconstrained seizures were checked by long‐term video‐EEG, and social seizures were characterized dependent on the Racine scale. Consistent 1‐Hz LFS‐EPN started on the third day after cathode implantation and was constrained by a multi‐channel trigger. Incitement proceeded until the rodents had no seizures for three sequential days.
Reference link- https://onlinelibrary.wiley.com/doi/10.1002/acn3.51214
