Vaccine booster after Johnson & Johnson-Janssen priming are safe and immunogenic
1. Both the Johnson & Johnson-Janssen (JJJ) and mRNA boosters provided an acceptable safety...
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2MM
#VisualAbstract: Pertuzumab plus trastuzumab significantly improves survival in metastatic breast cancer
Click to read this study in JAMA Network Open.
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Neonatal hypoglycemia not significantly associated with lower educational achievement during childhood
1. In this prospective cohort study neonatal hypoglycemia was not significantly associated with...
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Cardiosphere-derived cell therapy slows disease progression in Duchenne muscular dystrophy
1. Cardiosphere-derived cell therapy (CAP-1002) slowed loss of upper limb function by 71% compared...
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Multiple factors impact racial and ethnic disparities in opioid use disorder treatment during pregnancy
1. This study found minorities are diagnosed with opioid use disorder on average 37 days later...
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Donidalorsen reduces attacks in patients with C1 inhibitor deficiency
1. Patients with hereditary angioedema receiving donidalorsen showed reduced rates of angioedema...
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mRNA vaccine boosters less effective against the omicron variant in Qatar
1. mRNA booster vaccines for Covid-19 were highly effective against delta infection but less...
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#VisualAbstract: Immunocompromised individuals may be at an increased risk of metastses with cutaneous squamous cell carcinomas
Click to read this study in the Journal of the American Academy of Dermatology.
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Tranexamic acid is unlikely to induce signs suggestive of cerebral ischemia in the treatment of acute intracerebral hemorrhage: TICH-2 study
1. Patients presenting with acute intracerebral hemorrhage were not more likely to have...
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Increased risk of intracranial hemorrhage with aspirin and unfractionated heparin use for endovascular stroke treatment
1. Ischemic stroke patients assigned to aspirin-only, heparin-only, or both, had worse Modified...
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Pembrolizumab as a promising treatment in patients with classic or endemic Kaposi’s sarcoma
1. Treatment with pembrolizumab yielded a best overall response rate of 71%. 2. Adverse events...
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Ribociclib in addition to letrozole increases overall survival compared to letrozole alone
1. Overall survival was longer in the group receiving ribociclib with letrozole as compared with...
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Percutaneous transforaminal endoscopic discectomy non-inferior to open microdisctectomy
1. Percutaneous transforaminal endoscopic discectomy (PTED) was non-inferior to open...
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Kratom use disorder and withdrawal may be common in the United States
1. Preliminary data from a convenience sample of kratom users noted that current kratom use...
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Valoctocogene roxaparvovec gene therapy efficacious for hemophilia A treatment
1. The adeno-associated virus 5 (AAV5)-based gene therapy, valoctocogene roxaparvovec...
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Rucaparib compared to standard-of-care chemotherapy showed promising clinical and safe response to treat BRCA1 or BRCA2 mutated, relapsed ovarian carcinoma
1. The median progression-free survival was 7.4 months in the rucaparib group and 5.7 months in...
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Iberdomide elicits SRI-4 response in patients with systemic lupus erythematosus
1. More patients with systemic lupus erythematosus (SLE) who received high doses of iberdomide...
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Hospitalized Covid-19 patients from socially vulnerable neighborhoods have greater illness severity
1. Hospitalized Covid-19 patients presenting from socially vulnerable neighborhoods had greater...
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Telehealth may increase access to substance use treatment during COVID-19
1. Telehealth visits may be beneficial to patients with opioid use disorders, especially during...
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Rates of recurrent ischemic stroke among young adults with prior embolic stroke of undetermined source– the Young ESUS longitudinal cohort study
1. In patients with prior history of embolic stroke of undetermined source, there was a relatively...
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