#VisualAbstract: Peanut oral immunotherapy desensitizes young children with non-anaphylactic peanut allergies
Compared to placebo, children who received peanut oral immunotherapy experienced significantly...
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2MM
Combination treatment with varenicline and nicotine patch improves smoking cessation outcomes for concurrent alcohol users
1. In this randomized controlled trial, combined treatment with varenicline and nicotine patch...
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#VisualAbstract: Endotracheal intubation offers no benefit over supraglottic airway in patients with out-of-hospital return of spontaneous circulation
Rates of sustained return of spontaneous circulation after non-traumatic out-of-hospital cardiac...
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Melioidosis outbreak is associated with imported aromatherapy spray
1. Melioidosis, caused by Burkholderia pseudomallei, is rarely diagnosed in the US, and patients...
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Reliever-triggered inhaled glucocorticoid therapy in among Black and Latinx adults with asthma
1. Provision of an inhaled glucocorticoid and instruction on its use led to a significantly lower...
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#VisualAbstract: No difference in survival between fluorouracil, cisplatin, or carboplatin-based paclitaxel therapy for locally advanced esophageal squamous cell carcinoma
Click to read this study in JAMA Network Open.
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Tremor and memory symptoms prior to diagnosis demonstrate the strongest associations with subsequent Parkinson disease
1. In a diverse population with universal access to health care, tremor and impaired memory...
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Faricimab noninferior to aflibercept for treatment of neovascular age-related macular degeneration
1. In both trials, faricimab was demonstrated to be non-inferior to aflibercept at improving...
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Cardiorespiratory fitness may have an inverse dose-response relationship with adverse outcomes
1. This study demonstrated an inverse dose-response association between cardiorespiratory fitness...
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Clinically important troponin I threshold for mortality after cardiac surgery
1. For patients undergoing only a coronary-artery bypass grafting (CABG) or aortic-valve...
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#VisualAbstract: Delayed receipt of adjuvant hormone therapy is associated with worse survival in HR⁺, ERBB2- breast cancer
Click to read this study in JAMA Network Open.
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Intensive blood pressure control associated with increased cerebral blood flow in patients with hypertension – the SPRINT trial
1. In patients with hypertension, intensive blood pressure control to a target of less than 120...
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Faricimab may improve visual acuity in patients with diabetic macular edema
1. Faricimab every 8 weeks and faricimab per personalized treatment interval (PTI) were...
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2 Minute Medicine Rewind March 7, 2022
Association between Treatment for Localized Prostate Cancer and Mental Health Outcomes 1. No...
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Prophylactic nirsevimab protects infants from respiratory syncytial virus infection
1. Single-dose intramuscular injection of nirsevimab significantly reduced respiratory syncytial...
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Impact of changes in guidelines for management billing codes guidelines
1. Guidelines changes to frequently used outpatient evaluation and management (E/M) billing use...
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Pertuzumab has clinical benefits in metastatic breast cancer but is not cost-effective
1. The incremental cost-effectiveness ratio of the pertuzumab group was $436,679 per QALY gained....
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AD26.COV2.S vaccine provides protection against Covid-19
1. The AD26.COV2.S vaccine provided protection against moderate to severe-critical Covid-19. 2....
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Biosimilar HD201 has equivalent efficacy to trastuzumab in the treatment of ERBB2-positive (HER2) breast cancer
1. Total pathological complete response was not significantly different between trastuzumab and...
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