#VisualAbstract: Semaglutide improves symptoms in patients with heart failure
1. In this randomized controlled trial, in patients with heart failure with preserved ejection...
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2MM
Repeat transcatheter aortic valve replacement after initial attempt is generally safe in patients with balloon-expandable valves
1. Redo-TAVR had low procedural complication rates and was comparable to native-TAVR in terms of...
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Impact of vaccination against severe COVID-19 in the French population aged 50 years and above
1. In this retrospective population-based study, vaccination against COVID-19 among those over age...
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Chronic high-intensity interval training and moderate-intensity continuous training increase maximum fat oxidation in adults with overweight and obesity
Bookmark1. In this meta-analysis, both high-intensity interval training and moderate-intensity...
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Dexamethasone does not improve tuberculous meningitis survival in HIV
Bookmark1. In this randomized controlled trial, compared to placebo, dexamethasone did not improve...
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Optical coherence tomography guidance beneficial for managing coronary bifurcation lesions
Bookmark1. In this randomized controlled trial, percutaneous coronary intervention (PCI) performed...
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Spesolimab may improve quality of life in patients with generalized pustular psoriasis flares
Bookmark1. Efficacy of spesolimab appeared to be dose-dependent with high-dose spesolimab leading...
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Concurrent stereotactic radiation with antibody-drug conjugates in the treatment of brain metastases is associated with a greater risk of symptomatic radiation necrosis
Bookmark1. A greater percentage of patients who received concurrent stereotactic radiation therapy...
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Amivantamab Plus Chemotherapy with and without Lazertinib in EGFR-mutant NSCLC
Bookmark1. Progression-free survival was 6.3 months for the amivantamab–chemotherapy group, 8.3...
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Esketamine augmentation therapy is superior to quetiapine for treatment-related depression
Bookmark1. In this randomized controlled trial, in patients with treatment-resistant depression...
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Tight versus liberal blood glucose control results in similar ICU outcomes
Bookmark1. In this randomized controlled trial, tight versus liberal blood glucose control...
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Extrauterine placental perfusion and oxygenation in infants with very low birth weight
Bookmark1. This randomized clinical trial showed that very low birth weight (VLBW) infants who...
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Structured exercise interventions led to improvements in mild to moderate mental health problems in adolescents
Bookmark1. In this systematic review, adolescents (aged 10-19 years) showed clinical improvements...
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#VisualAbstract: Trial of Botulinum Toxin for Isolated or Essential Head Tremor
Bookmark Click here to read this study in NEJM. VA design by Bryan Sun. ©2023 2 Minute Medicine,...
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Semaglutide improves symptoms in patients with heart failure
Bookmark1. In this randomized controlled trial, in patients with heart failure with preserved...
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#VisualAbstract: Treatment of metastatic uveal melanoma with tebentafusp compared to standard treatment
Bookmark 1. Median overall survival and progression-free survival were greater in the tebentafusp...
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Probiotics not effective in decreasing incidence of acute otitis media in children
Bookmark1. This randomized placebo-controlled clinical trial found that the daily use of...
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#VisualAbstract: Osimertinib with or without Chemotherapy in EGFR-Mutated Advanced Non-Small Cell Lung Cancer (NSCLC)
Bookmark Click here to read this study in NEJM. VA design by Bryan Sun. ©2023 2 Minute Medicine,...
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Solanezumab does not slow cognitive decline in patients with Alzheimer’s disease
Bookmark1. In this randomized controlled trial, over a period of 240 weeks, solanezumab did not...
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Pyrotinib in combination with trastuzumab and docetaxel promising for HER2 positive metastatic breast cancer
Bookmark1. This phase 3 randomised trial demonstrated that compared with placebo in combination...
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