Rectal cancer presentation and screening rates during the COVID-19 pandemic
Bookmark1. Despite the decrease in colonoscopies performed at the start of the COVID-19 pandemic,...
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2MM
#VisualAbstract: Prehospital Tranexamic Acid for Severe Trauma
BookmarkClick to read the study in The New England Journal of Medicine ©2023 2 Minute Medicine,...
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Antidepressants are effective in patients with comorbid depression and medical diseases
Bookmark1. This umbrella systematic review and meta-analysis found that depression rating scale...
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Adjunctive antidepressant maintenance ineffective in bipolar I depression
Bookmark1. In this randomized controlled trial, adjunctive treatment with escitalopram or...
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Prenatal magnesium at 30-34 weeks does not reduce risk of death or cerebral palsy: MAGENTA trial
Bookmark1. Efficacy: There was no significant difference in death or cerebral palsy at 2 years...
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Oral semaglutide effectively reduces bodyweight in non-diabetic adults with obesity
Bookmark1. The semaglutide 50 mg group saw a 15.1% reduction in body weight at 68 weeks compared...
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#VisualAbstract: Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2)
BookmarkClick here to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved....
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Retatrutide effectively reduces body weight in patients with obesity
Bookmark1. In this randomized controlled trial, the triple-hormone-receptor agonist retatrutide...
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NaV1.8 inhibitor VX-548 reduces acute post-operative pain
Bookmark1. In this randomized controlled trial, the elective NaV1.8 inhibitor VX-548 reduced acute...
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#VisualAbstract: Antibody NI006 for treatment of transthyretin amyloid cardiomyopathy caused no serious adverse events
Bookmark©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without...
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Baricitinib is safe and effective for treatment of refractory juvenile idiopathic arthritis
Bookmark1. Time to disease flare was significantly shorter in the placebo group versus...
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Low-grade inflammation scores can help predict 90-day outcomes after stroke
Bookmark1. This retrospective cohort study found that higher low-grade inflammation (LGI) scores...
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#VisualAbstract: Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity
BookmarkClick here to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved....
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CRISPR-Cas9 promoting fetal hemoglobin production improves severe sickle cell disease
Bookmark1. In this randomized controlled trial, infusion of OTQ923 disrupted inhibitory HBG1 and...
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Video laryngoscopy leads to higher success on first intubation attempt than direct laryngoscopy
Bookmark1. In this randomized controlled trial, video laryngoscopy in the context of critically...
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#VisualAbstract: Low-dose glucocorticoids for rheumatoid arthritis do not increase blood pressure
Bookmark1. In this pooled analysis of randomized controlled trials, low-dose glucocorticoids...
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Religion and spirituality-based treatments are effective for mental health care
Bookmark1. In this meta-analysis of randomized controlled trials, religion and spirituality-based...
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Nivolumab/Ipilimumab vs Nivolumab Alone in Advanced Cancers Other Than Melanoma
Bookmark1. Pooled overall survival and progression-free survival HR were found to be 0.95 and 0.88...
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HPV vaccination is safe and effective at 10-year follow-up
Bookmark1. In a long-term follow-up study of an earlier randomized control trial, participants...
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Mindfulness-based elder care programs improve mental and spiritual health in residents of long-term care facilities
Bookmark1. In this randomized controlled trial, seniors with disabilities in long-term care...
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