Risk factors associated with cognitive impairment development in older adults
1. This longitudinal prospective cohort study found that older adults with trajectories involving...
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2MM
#VisualAbstract: Nonoperative management of unstable medial malleolus fractures is noninferior to operative management
Click here to read this study in JAMA Network Open. ©2024 2 Minute Medicine, Inc. All rights...
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Pembrolizumab and chemotherapy combination improves survival in advanced pleural mesothelioma
1. Patients in the pembrolizumab plus chemotherapy group reported a significantly greater overall...
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Machine-learning-based models found to have predictive abilities no better than chance in out-of-sample evaluations
1. Machine learning prediction models fared poorly when used across clinical trials 2. To improve...
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#VisualAbstract: Curcumin-piperine supplementation may lead to lower inflammation in post-stroke patients
1. Supplementation with curcumin-piperine resulted in significantly reduced serum levels of...
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#VisualAbstract: Perioperative Toripalimab Plus Chemotherapy Improves Event-Free Survival in Patients With Resectable Non–Small-Cell Lung Cancer
Click here to read this study in JAMA. ©2024 2 Minute Medicine, Inc. All rights reserved. No works...
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Wearing A Mask During High-Intensity Exercise Did Not Impact Hemodynamics During Exercise
1. In a healthy population, wearing a mask during high-intensity exercise does not change...
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#VisualAbstract: Azithromycin during routine well-infant visits does not prevent death in Burkina Faso
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works...
Read MoreMonocyte-to-HDL ratio may be an indicator of poor endothelial dysfunction in diabetics
1. This cross-sectional study is the first to identify the monocyte-to-HDL ratio (MHR) as an indicator of poor endothelial dysfunction in a sample of diabetic patients. Evidence Rating Level: 2 (Good) Endothelial disruption and...
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Vascular Function Improvements Derived From Exercise Are Not Sex-Dependent
1. The exercise training prevented increases in total cholesterol and LDL cholesterol which were...
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Liquefied petroleum gas stove use during pregnancy does not reduce stunting in infants
1. In this randomized controlled trial, replacing biomass stoves with those using liquefied...
Read MorePerinatal depression associated with threefold risk of suicidal behaviour
1. Perinatal depression (PND) was found to be associated with a 3-fold increased risk for suicidal behaviours compared to a non-PND cohort at 18-year follow-up. 2. PND most significantly increased risk for suicidal behaviours...
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Short-stay units may be viable alternatives for admission for acute heart failure
1. This multicentre, randomized, comparative effectiveness study found that the short-stay unit...
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Pembrolizumab Enhances Progression-Free Survival in HER2-Positive Gastro-Esophageal Cancer
Findings suggest that pembrolizumab, added to trastuzumab and chemotherapy, enhances...
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Increased vitamin C intake was associated with decreased aortic calcification
1. Higher dietary vitamin C intake was correlated with a reduction in abdominal aortic...
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Curcumin-piperine supplementation may lead to lower inflammation in post-stroke patients
1. Supplementation with curcumin-piperine resulted in significantly reduced serum levels of...
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Prolonged rituximab maintenance therapy does not provide overall survival benefit in low-burden follicular lymphoma
1. In patients with low tumor burden follicular lymphoma (LTBFL): Rituximab maintenance therapy...
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Optimizing Subtyping-Based Therapy in Triple-Negative Breast Cancer
1. The median progression-free survival was improved with the pooled subtyping-based therapy group...
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Probiotic supplementation may improve outcomes in patients with type 2 diabetes
1. Patients with type 2 diabetes randomized to using probiotic supplements were found to have...
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Radical cure with primaquine reduces risk of Plasmodium vivax parasitaemia in patients with Plasmodium falciparum infection
1. Patients in the primaquine group reported a significant reduction in parasitemia risk at day 63...
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