Intensive blood pressure lowering by non-physician healthcare providers significantly reduces the risk of cardiovascular disease
1. A significant reduction in all-cause mortality was seen among patients in the intervention...
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2MM
Metformin use may decrease risk of osteoarthritis development
1. In this retrospective cohort study, individuals with diabetes treated with metformin had a...
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#VisualAbstract: Hydrochlorothiazide does not impact risk of kidney-stone recurrence
1. In this randomized controlled trial, among patients with recurrent kidney stones,...
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Childhood maltreatment may cause mental health problems
1. In this systematic review and meta-analysis of quasi-experimental studies, there was a moderate...
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Exhaled volatile organic compounds predict bronchopulmonary dysplasia in preterm infants
1. Exhaled volatile organic compounds (VOCs) at day 3 and day 7 of life in preterm infants (<30...
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Expectant management of patent ductus arteriosus noninferior to early ibuprofen use
1. In this randomized controlled trial, expectant management of patent ductus arteriosus (PDA) in...
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Lebrikizumab effective in treating moderate-to-severe atopic dermatitis
1. In two phase three trials, 16 weeks of lebrikizumab treatment effectively treated adolescents...
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Hyperfractionated radiotherapy reduces complication rates compared to standard fractionation for locally advanced nasopharyngeal carcinoma
1. Fewer patients in the hyperfractionation group reported grade 3 or worse late radiation-induced...
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SAR-CoV-2 infection during pregnancy may lead to adverse neurodevelopmental outcomes in male offspring
1. In this retrospective cohort study of infants exposed to SARS-CoV-2 in utero, there was a...
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Spirituality may help patients with weight management after bariatric surgery
1. In this cross-sectional study, spiritual practices such as yoga, meditation, and being involved...
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Molnupiravir and nirmatrelvir-ritonavir reduce COVID-19 mortality in hospitalized patients
1. In this trial emulation study, molnupiravir and nirmatrelvir-ritonavir reduced all-cause...
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Febuxostat may be effective in preventing contrast-induced acute kidney injury
1. This randomized control trial found that febuxostat has a reno-protective effect that can...
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Palliative care improves satisfaction in patients with progressive neurologic diseases and their caregivers
1. In this systematic review and meta-analysis, palliative care helped alleviate symptom burden...
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Immediate postpartum opioid administration not associated with adverse infant outcomes
1. No association was found between maternal opioid treatment in the immediate postpartum period...
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No difference in complete expulsion of intrauterine device between early and standard interval postpartum placement
1. In this randomized clinical trial, participants underwent postpartum intrauterine device (IUD)...
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Past infection with pre-omicron variants of COVID-19 protects against re-infection
1. Past infection with ancestral, alpha, beta, and delta variants of COVID-19 had a protection...
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Abnormal menstruation may be associated with worse cardiometabolic outcomes later in life
1. In this large retrospective matched cohort study of women aged 18-40 years, a history of...
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United States patients receive subcutaneous fluids less frequently than intravenous fluids when compared to Canadian patients
1. Canadian patients receive subcutaneous administration of medications and/or fluids more...
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Alternative Dose Regimens of Exemestane in Postmenopausal Women with Breast Cancer
1. Through the reduction in serum estradiol, there was noninferiority between the 3-times-weekly...
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#VisualAbstract: Secukinumab reduces symptoms of moderate-to-severe hidradenitis suppurativa
1. Patients receiving secukinumab every 2-weeks showed superior clinical response rates compared...
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