#VisualAbstract: Adjuvant pembrolizumab improves distant metastasis-free survival in stage IIB-C melanoma
Click to read this study in The Lancet Oncology.
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2MM
Serum glial fibrillary acidic protein may be a useful prognostic marker of disease progression in multiple sclerosis
1. Patients with progressive multiple sclerosis were more likely to have elevated levels of serum...
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Telephone health coaching intervention ineffective for improving outcomes for hypertension
1. A randomized trial for a blood pressure (BP) self-management program, involving 6 months of...
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Spirituality has mixed effects on outcomes in ALS patients and caregivers
1. In this scoping review, qualitative studies on amyotrophic lateral sclerosis (ALS) demonstrated...
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Anthracycline may be associated with increased incidence of heart failure
1. For patients with a history of lymphoma or breast cancer, anthracycline use is associated with...
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Glucagon-like peptide-1 receptor agonist may reduce incidence of diabetic retinopathy
1. Patients with Type 2 Diabetes taking glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have...
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Baxdrostat reduces blood pressure in previously treatment-resistant hypertension
1. Compared to placebo, baxdrostat showed a dose-dependent reduction in blood pressure in patients...
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Meningococcal group B vaccine effective at preventing meningococcal disease in children
1. In this case-control study, complete vaccination with meningococcal group B vaccine in children...
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Study details side effects of alpha-2-adrenergic agonists for treating ADHD in preschool children
1. In a retrospective cohort study, the use of alpha-2-adrenergic agonists to treat...
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COVID-19 mRNA vaccines are safe and effective in children aged 5 to 11 years
1. In a systematic review and meta-analysis of randomized trials and cohort studies in children 5...
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Machine renal perfusion reduces delayed graft function after transplantation
1. In this randomized controlled trial, machine perfusion of the kidney reduced delayed graft...
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Momelotinib reduces symptom burden compared to danazol in patients with myelofibrosis
1. After a 24-week treatment period, a significantly greater proportion of patients randomized to...
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Molnupiravir does not reduce COVID-19-related hospitalizations in vaccinated adults
1. All-cause hospitalizations and deaths were reported in 1% of patients in the molnupiravir and...
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Clinical outcomes of chronic and acute pediatric osteomyelitis
Clinical outcomes of pediatric osteomyelitis 1. Pediatric patients under 18 years with chronic...
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Exercise improves outcomes in patients with cardiovascular disease
1. In this systematic review and meta-analysis, the addition of exercise to usual care in patients...
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Protein-truncating variants in apolipoprotein B and PCSK9 genes associated with lower exposure to atherogenic LDL cholesterol and risk of coronary heart disease
1. In this genetic association study, among 209 537 participants, a protein-truncating variant...
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Low-dose pirfenidone may be noninferior to standard dosing in patients with idiopathic pulmonary fibrosis
1. For patients with idiopathic pulmonary fibrosis (IPF), there was no difference in pulmonary...
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Former professional football players may be at greater risk of chronic disease
1. In this retrospective cohort study, there was an increased prevalence of age-, race-, and body...
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Faecal haemoglobin concentrations associated with mortality and cause of death in colorectal cancer screening
1. In this prospective cohort study, fecal hemoglobin concentration (f-Hb) was associated with...
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Abuse during childhood and young adulthood is linked to welfare receipt
1. Experiencing either physical abuse alone or both physical and sexual abuse before the age of 18...
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