Empagliflozin use is associated with slower progression of chronic kidney disease
1. Empagliflozin led to a lower risk of kidney disease progression in patients with chronic kidney...
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2MM
Chronic obstructive pulmonary disease associated with worse postoperative outcomes
1. Patients with chronic obstructive pulmonary disease (COPD) had lower survival rates and greater...
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#VisualAbstract: Adagrasib provides antitumour activity against KRAS G12C mutant metastatic colorectal cancer both as monotherapy and in combination with cetuximab
Overall tumour response to monotherapy treatment with adagrasib was 23% 46% in combination with...
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Plant-based diets may be associated with lower risk of aggressive prostate cancer
1. In this prospective cohort study, greater consumption of healthful plant-based foods was...
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Deep intronic FGF14 repeat expansion associated with late-onset cerebella ataxia
1. A dominant deep-intron GAA repeat expansion in the FGF14 gene was found among French Canadian...
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Catheter ablation reduces rates of persistent atrial fibrillation and atrial tachyarrhythmia
1. In patients with untreated paroxysmal atrial fibrillation, catheter ablation was associated...
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Aspirin thromboprophylaxis noninferior to low-molecular-weight heparin in patients with fractures
1. In this randomized clinical trial, there were no differences in mortality, pulmonary embolism,...
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Bimekizumab is effective for active psoriatic arthritis in biologic-naïve adults
1. Significantly more patients in the bimekizumab group reached ACR50 at week 16 compared to the...
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Teach-back method effective to improve postpartum maternal-infant health
1. In a cohort of portpartum mothers with limited maternal health literacy, the teach-back...
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#VisualAbstract: Adjuvant capecitabine improves clinical outcomes in patients with locally advanced nasopharyngeal carcinoma
Click to read this study in JAMA Oncology.
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Torsemide not associated with significant difference in all-cause mortality over 12 months compared to furosemide – The TRANSFORM-HF randomized clinical trial
1. In this randomized clinical trial, among 2859 patients, death occurred in 26.1% of patients...
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Methylprednisolone after hip replacement surgery improves pain and sleep quality
1. In this randomized controlled trial, post-operative treatment with methylprednisolone was...
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#VisualAbstract: Tamoxifen increases the risk of endometrial cancer in premenopausal women with breast cancer
Click to read this study in JAMA Network Open.
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Machine-learning based prompts for serious illness conversations reduces end of life systemic therapy use
1. The proportion of patients receiving serious illness conversations (SICs) was increased in the...
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Melatonin improves sleep onset in children with autism spectrum disorder
1. In this randomized controlled trial, sleep onset latency was significantly decreased in...
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Intranasal corticosteroids no better than saline in treating pediatric sleep-disordered breathing
1. In a randomized controlled trial of children with sleep-disordered breathings, intranasal...
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Futibatinib for FGFR2 Mutated Intrahepatic Cholangiocarcinoma
1. Using futibatinib to treat patients with FGFR mutated intrahepatic cholangiocarcinoma resulted...
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Combined visual-olfactory training for COVID-19 resultant olfactory loss
1. Participants with post-viral olfactory dysfunction (PVOD) who underwent olfactory training (OT)...
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Time-restricted eating ineffective for weight loss
1. Time-restricted eating was not an effective strategy for long-term weight loss in a general...
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Telehealth treatment is effective in managing behavior problems in children with developmental delay
1. In a randomized clinical trial, internet-delivered parent-child interaction therapy (iPCIT)...
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