Vitamin C supplementation in pregnant smokers leads to improved airway function in offspring
1. In this multi-center randomized controlled trial, vitamin C supplementation in pregnant women,...
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2MM
Comparison of resuscitative endovascular balloon occlusion of the aorta versus resuscitative thoracotomy for aortic occlusion
1. This multicentre, comparative effectiveness study demonstrated that aortic occlusion via...
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Beremagene geperpavec improves wound healing in dystrophic epidermolysis bullosa
1. Topical gene therapy beremagene geperpavec (B-VEC) was superior to placebo in achieving...
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No significant differences in postoperative complications found between open repair with local anesthesia and laparoscopic repair of inguinal hernias
1. In this retrospective cohort study, among 107 073 patients, no significant difference was found...
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Ferric derisomaltose may reduce heart failure-related hospitalizations
1. Risk of hospital admission was lower in the ferric derisomaltose group versus usual care. 2....
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Emergency department crowding negative influences outcomes for adults presenting with asthma
1. Amongst patients presenting to the emergency department with acute asthma exacerbations,...
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Surgical bypass for chronic limb-threatening ischemia reduces risk of adverse limb events
1. In patients with chronic limb-threatening ischemia, major adverse limb events and mortality...
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Suffocation and unexplained infant death risks differentially affected by safe sleep practices
1. A case-control study utilizing publically available databases of sudden infant deaths and...
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Emraclidine is safe and well-tolerated for the treatment of schizophrenia
1. Incidence of total adverse events and specific adverse events were similar between the...
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Dexemedomidine premedication increases preoperative sedation and inhibits stress induced by tracheal intubation
1. The use of oral dexmedetomidine as premedication prior to neurosurgery increased preoperative...
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Patient-supporter training improved patient confidence in managing diabetes
1. In this randomized control trial, providing positive support technique training to...
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Medical masks do not demonstrate definitive noninferiority to N95 respirators in preventing COVID-19
1. This randomized controlled trial did not definitively demonstrate noninferiority between N95...
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Evolving standard of care guidelines have improved outcomes in hospitalized COVID-19 patients
1. Within the Adaptive COVID-19 Treatment Trial (ACCT) series, improvement in standard of care...
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Medicaid is a long-term source of insurance coverage for low-income families
1. In this cohort study, over half of all beneficiaries of Medicaid in 2011 were still enrolled...
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Direct-acting antiviral agents significantly lower Hepatitis C related mortality and cancer risk
1. In this retrospective cohort study, adult patients with hepatitis C virus (HCV) infection...
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Sulthiame may be a safe and effective medication for severe obstructive sleep apnea
1. In this randomized controlled trial, sulthiame was shown to be a safe oral medication that can...
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Double embryo transfer may be associated with neonatal risks
1. In a large Swedish cohort of singleton births following the use of assisted reproductive...
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Tumor-infiltrating lymphocyte therapy compared to ipilimumab in advanced melanoma
1 .Tumor-infiltrating lymphocytes therapy shows improvements in PFS when compared to ipilimumab 2....
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Positive prostate MRI and targeted biopsy reduce the detection of clinically insignificant prostate cancer
1. Fewer instances of clinically insignificant prostate cancer were identified in an experimental...
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Variations in the use of cemented implants for hip fracture repair in Nova Scotia
1. In this retrospective observational study, there were significant between-hospital and...
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