Esketamine as an adjunct with propofol and fentanyl to avoid perioperative hypotension
1. The use of esketamine in combination with propofol significantly reduced the risk of...
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2MM
Diet, substance use, and physical activity and their effects on mental health outcomes
1. A healthy lifestyle defined by diet, smoking status, physical activity, alcohol consumption,...
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Eating only during the day protected against mood vulnerability during circadian disturbances
1. In this study, participants eating both during the day and night had increased depression and...
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Ipilimumab addition to nivolumab showed no significant clinical benefit in resected advanced stage melanoma
Ipilimumab addition to nivolumab showed no significant clinical benefit in resected advanced stage...
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Low income associated with increased BMI and chronic stress
1. In a prospective cohort study, low income was associated with an increase in body mass index...
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Letrozole and abemaciclib in estrogen receptor–positive recurrent endometrial cancer
1. Almost half of patients (47%) had either an objective response or had progression free survival...
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Fulvestrant for treatment of estrogen receptor-positive, HER2-negative advanced breast cancer may improve progression free survival using ESR1 mutation as guidance
1. Median progression free survival was longer in the fulvestrant and palbociclib group compared...
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Intravenous immune globulin improved disease severity in dermatomyositis
1. Patients with dermatomyositis treated with intravenous immune globulin (IVIG) were more likely...
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Cerebral embolic protection during transcatheter aortic-valve replacement does not reduce the incidence of stroke
1. In patients with aortic stenosis undergoing transcatheter aortic valve replacement (TAVR), the...
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Anti-TNF for inflammatory bowel disease after 24 weeks of pregnancy does not affect neonatal outcomes
1. Patients who continued anti-tumor necrosis factor (TNF) after 24 weeks of pregnancy had...
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Maternal consumption of ultra-processed foods associated with increased risk of obesity in offspring
1. Ultra-processed food consumption by mothers during child rearing period was found to be...
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Aerobic and strengthening physical activity may have a dose-response association with mortality
1. In this study, compared to no aerobic physical activity (PA), substantial mortality risk...
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Adjunctive glucose-lower therapies do not decrease risk of microvascular complications in diabetic patients
1. No significant differences in vascular complications of diabetes were seen in patients using...
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Factors associated with anticoagulation discontinuation in palliative care patients
1. The decision to discontinue anticoagulation in palliative care patients was not strongly...
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Roflumilast cream superior to vehicle cream in the treatment of plaque psoriasis – the DERMIS-1 and DERMIS-2 trials
1. Treatment of plaque psoriasis with roflumilast cream was associated with better clinical...
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Risk of hip fracture in meat-eaters, pescatarians, and vegetarians
1. In a cohort of UK-based women, vegetarians/vegans, but not occasional meat-eaters or...
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Regular physical activity may confer protection against adverse COVID-19 outcomes
1. In this study, engaging in regular physical activity had a lower risk of infection,...
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Impact of multispecies probiotic in preventing antibiotic-associated diarrhea unclear
1. In a randomized control trial, administration of multispecies probiotics did not affect the...
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Selpercatinib continues to demonstrate effective response in RET fusion-positive NSCLC
1. Selpercatinib was found to have similar effective objective response rates compared to past...
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Selpercatinib showed promising clinical activity in tumour-agnostic patients with RET fusion-positive cancers other than thyroid and lung cancer
1. Objective response rate was 43.9%. Patients treated with selpercatinib also experienced...
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