Glargine and liraglutide are effective glucose-lowering medications in type 2 diabetes
1. Compared to sitagliptin and glimepiride, glargine and liraglutide were more effective in...
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2MM
More permissive parameters for active surveillance eligibility is potentially possible in slow-growing thyroid cancers
1. Patients in the active surveillance group who had forgone surgery had no difference in survival...
Read MoreIncreased pre-chemotherapy inflammatory biomarkers (IL-6 and CRP) correlated to increased risk of frailty post-chemotherapy in older breast cancer patients
1. 25.8% of patients receiving chemotherapy for breast cancer experienced worsening frailty status. 2. Patients with both biomarkers (IL-6 and CRP) elevated before chemotherapy had a significantly higher risk of decline in...
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Dapagliflozin slows disease progression in patients with heart failure with preserved ejection fraction
1. Dapagliflozin was shown to reduce the risk of disease progression and cardiovascular death in...
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Tofersen does not improve ALS symptoms in patients with SOD1 mutations
1. In patients with amyotrophic lateral sclerosis (ALS) and superoxide dismutase 1 (SOD1)...
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Effectiveness of stand-alone telephone-delivered intervention for reducing problem alcohol use
1. In this randomized controlled trial, in participants with problem alcohol use, individuals in...
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Occupational and leisure physical activity may have varying effects on inflammation
1. Lower leisure time physical activity and higher occupational physical activity were associated...
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Study details use of inhaled nitric oxide in extremely premature infants in Japan
1. Between 2003 to 2016, there was an increase in both survival and the use of inhaled nitric...
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#VisualAbstract: Induction chemotherapy with erlotinib does not improve survival in stage III-IV head and neck squamous cell carcinoma
Click to read this study in Clinical Cancer Research.
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Unsupervised online yoga transiently improves symptoms in patients with knee osteoarthritis
1. Compared to a control group, patients with knee osteoarthritis who engaged in online yoga had...
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Dupilumab plus topical corticosteroids are effective in the treatment of childhood atopic dermatitis
1. By week 16, 28% of patients in dupilumab reported clear or almost clear skin (IGA 0-1) compared...
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Empagliflozin use associated with decreased rate of macroalbuminuria
1. In this post-hoc analysis of a randomized controlled trial, empagliflozin use in patients with...
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#VisualAbstract: Adjuvant pembrolizumab increased disease-free survival in completely resected, PD-L1 unselected non-small-cell lung cancer patients
1. Adjuvant pembrolizumab significantly improved disease-free survival in comparison to placebo in...
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Lower limb osteoarthritis may be more prevalent in retired Olympians
1. In this study, one in four retired Olympians reported physician-diagnosed osteoarthritis (OA),...
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#VisualAbstract: Polypill reduces adverse cardiovascular events among older patients with recent myocardial infarction
Click here to read this study in NEJM.
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Risk of cardiovascular pathology determined using advanced cardiovascular imaging limited by heterogeneity amongst patients with human immunodeficiency virus
1. Prevalence of moderate coronary disease ranged from 0-52% amongst patients with human...
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Rare genetic variants may be enriched in patients with high-risk spontaneous coronary artery dissection
1. This prospective case-control study demonstrated that approximately 20% of patients with...
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Sleep surgery for obstructive sleep apnea may decrease blood pressure
1. In this systematic review and meta-analysis, surgeries for sleep apnea showed improvements in...
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Bihormonal artificial pancreas effective for post total pancreatectomy patients
1. In patients that developed diabetes following total pancreatectomy, those using bihormonal...
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Adjuvant pembrolizumab increased disease-free survival in completely resected, PD-L1 unselected non-small-cell lung cancer patients
1. Adjuvant pembrolizumab significantly improved disease-free survival in comparison to placebo in...
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