Low- to moderate-intensity exercise for 1 hour attenuates lipid levels and insulin resistance
1. This randomized controlled trial found that compared to no exercise, low-intensity exercise on...
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Mirvetuximab soravtansine-gynx compared to chemotherapy in folate receptor alpha-positive platinum resistant ovarian cancer led to improved survival
1. Mirvetuximab soravtansine-gynx (MIRV), significantly improved progression-free survival,...
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Atezolizumab Monotherapy vs Chemotherapy In Advanced Urothelial Carcinoma
1. The median overall survival was similar between both groups, 15.2 months in atezolizumab...
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Glucagon-like peptide 1 receptor agonists (GLP-1RAs) prescribed for type 2 diabetes are associated with reduced colorectal cancer (CRC) risk compared to other antidiabetic agents
1. In all patients, there was a 44% reduction in risk of colorectal cancer when using GLP-1RAs as...
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#VisualAbstract: Ibrutinib-Venetoclax Improves Progression-Free Survival in Chronic Lymphocytic Leukemia
Click here to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved. No...
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Low income associated with worse cardiovascular health in middle-aged adults
1. In this cross-sectional study, low-income middle-aged adults in the United States had increased...
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#VisualAbstract: Low-dose amitriptyline effective and well-tolerated for management of irritable bowel syndrome
1. Low-dose amitriptyline was associated with a marked decrease in IBS-SSS score at 6 months...
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Weekly insulin icodec is more effective than daily basal insulin at reducing HbA1c
1. In this randomized controlled trial, insulin icodec demonstrated superior HbA1c reduction as...
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Levothyroxine does not improve heart transplantation rates in brain-dead donors
1. In this randomized crossover trial, intravenous levothyroxine, given to hemodynamically...
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No increase in mortality with paclitaxel-coated devices among patients with femoropopliteal disease
1. There was no significant increase in mortality between the paclitaxel-coated and control...
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A low-inflammatory diet is associated with a lower incidence of diabetes
1. Consumption of a diet consisting of more foods with low inflammatory diet index (IDI) was...
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Traffic-related air pollution is associated with increased blood pressure
1. In this randomized crossover trial, mean systolic and diastolic blood pressures were higher for...
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Tiragolumab Combo Fails to Improve Survival in Untreated Extensive-Stage SCLC
1. Median PFS and OS between the tiragolumab and control arms were similar 2. Treatment-related...
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Current expert consensus for the treatment of adult patients with drug reaction with eosinophilia and systemic symptoms
1. A large majority of experts in this study came to a unified consensus on how to approach the...
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Levothyroxine IV in Brain-Dead Heart Donors Shows No Benefit, Raises Health Risks
1. In this randomized crossover trial, intravenous levothyroxine, given to hemodynamically...
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Methotrexate Reduces Pain in Inflammatory Hand Osteoarthritis
1. Methotrexate 20 mg once weekly resulted in significant pain reduction among patients with hand...
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Recurrence is high in patients with transient atrial fibrillation during hospitalization
1. In this matched cohort study, approximately one in three patients who had transient new-onset...
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COVID virologic rebound may occur in patients treated with nirmatrelvir-ritonavir
1. In this retrospective cohort study, the virologic rebound (VR) of coronavirus disease 2019...
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Paclitaxel-Coated Devices Do Not Increase Mortality Risk for Patients With Femoropopliteal Disease
1. There was no significant increase in mortality between the paclitaxel-coated and control...
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Low-Inflammation Diet Linked With Lower Risk for Diabetes
1. Consumption of a diet consisting of more foods with low inflammatory diet index (IDI) was...
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