#VisualAbstract: Maintenance endocrine therapy plus bevacizumab after induction with paclitaxel is effective for ER+ breast cancers
Click to read this study in The Lancet Oncology.
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2MM
Vaccination after recovery from COVID-19 reduced rate of reinfection by half
1. Completion of the primary vaccination series against COVID-19 amongst individuals who had...
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Comprehensive telehealth intervention effective for reducing HbA1c in poorly controlled diabetes
1. In this randomized controlled trial, a comprehensive telehealth intervention was linked to a...
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#VisualAbstract: Vitamin D supplementation does not reduce the risk of incident fractures among healthy adults
Click here to read this study in NEJM.
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Comparison of systemic corticosteroids with and without nebulized budenoside for management of severe acute asthma
1. Inhaled corticosteroid administration with systemic corticosteroid in acute asthma...
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#VisualAbstract: Once-weekly cisplatin is noninferior to cisplatin every 3 weeks for postoperative head and neck cancers
Click to read this study in the Journal of Clinical Oncology.
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Methotrexate reduces functional burden of disease in patients with arthralgia at-risk of developing rheumatoid arthritis
1. Compared to placebo, methotrexate did not significantly reduce the risk of the development of...
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Association between early left ventricular ejection fraction improvement after transcatheter aortic valve replacement and 5-Year clinical outcomes
1. In this retrospective cohort study, left ventricular ejection fraction (LVEF) improvement at 30...
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Increased maternal milk feeding associated with improved neurodevelopmental outcomes for former preterm infants
1. A higher dose of maternal milk during the critical period from very preterm birth to...
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#VisualAbstract: Nonoperative management of uncomplicated acute appendicitis comparable to appendectomy but leads to increased length of stay and disease recurrence
1. No significant differences in treatment success and rate of adverse events were detected in 8...
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Early differences in growth and adiposity among offspring conceived using assisted reproductive technology attenuated by late adolescence
1. In this cohort study, among 158,066 individuals, offspring conceived by assisted reproductive...
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Association Between CYP Metabolizer Phenotypes and SSRI Induced Weight Gain
1. In this retrospective cohort study, in patients prescribed citalopram, poor/intermediate...
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Nonoperative management of uncomplicated acute appendicitis comparable to appendectomy but leads to increased length of stay and disease recurrence
1. No significant differences in treatment success and rate of adverse events were detected in 8...
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Demographic trends in heart failure related mortality over past 2 decades
1. In this retrospective cohort analysis, heart failure (HF) related mortality has increased in...
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Resuscitation practices in moderate and late preterm infants are highly variable
1. Between 2011 and 2020 there was an increase in non-invasive resuscitation interventions and a...
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Early left ventricular ejection fraction improvement post transcatheter aortic valve replacement associated with improved 5-year clinical outcomes
1. This cohort study demonstrated that among patients with severe aortic stenosis and left...
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Dapagliflozin associated with reduced risk of cardiovascular and kidney outcomes irrespective of background use of cardiovascular medications
1. In this secondary analysis of the DECLARE-TIMI 58 trial, among 17,160 patients, dapagliflozin...
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Dinoprostone superior to Foley catheter balloon induction for patients with prior C-section
1. For patients with one prior C-section, the induction of labour to delivery time was 10 hours...
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#VisualAbstract: Treatment with 4% albumin post cardiac surgery does not reduce adverse events compared to Ringer acetate
Click to read this study in JAMA.
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