Exposure to macrolides in children may be potentially associated with sensorineural hearing loss
1. Patients under 18 years of age with sensorineural hearing loss (SNHL) had a higher odds of...
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2MM
4% albumin solution nonsuperior to Ringer acetate for volume replacement in cardiac surgery with cardiopulmonary bypass
1. Rates of adverse outcomes amongst cardiac surgery patients randomized to receive either Ringer...
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#VisualAbstract: High-flow nasal cannula is non-inferior to continuous positive airway pressure among acutely ill children
Click to read this study in JAMA.
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Use of left ventricular assist device associated with increased mortality compared to intra-aortic balloon pump in patients with cardiogenic shock from myocardial infarction
1. Use of an intravascular left ventricular assist device was associated with higher mortality in...
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Omecamtiv mecarbil not associated with improved exercise capacity compared with placebo in patients with chronic heart failure with reduced ejection fraction
1. In this randomized controlled trial, among 276 patients with chronic heart failure with reduced...
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Increasing anesthesiologist coverage responsibilities associated with increased surgical patient mortality and significant morbidity
1. This retrospective cohort study with 866 453 adults demonstrated that as overlapping...
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Alcohol recovery narratives are dynamic and may be composed of multiple dimensions
1. In this study, the eight principle narrative dimensions related to alcohol recovery identified...
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Pembrolizumab plus chemotherapy improved survival in a subgroup of triple-negative metastatic breast cancer
1. Pembrolizumab plus chemotherapy for triple-negative breast cancer significantly increased PFS...
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The Pfizer-BioNTech vaccine confers moderate protection against COVID-19 in children
1. Two doses of the Pfizer-BioNTech vaccine resulted in moderate protection against SARS-CoV-2...
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Low-dose AAVS3 gene therapy is efficacious for treating patients with hemophilia B
1. Hemophilia B patients treated with the adeno-associated virus (AAV) gene therapy produced...
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Prenatal exposure to opioids and its potential associations with subsequent academic performance
1. Any exposure to opioid analgesics prenatally was not associated with differences in scholastic...
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Wishes and needs of nursing home residents are heterogeneous and comprise various themes
1. Wishes and needs of nursing home residents were assigned to 12 different themes, the most...
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Uptake of hepatitis C treatment in people who inject drugs associated with decreased liver disease
1. Hepatitis C patients with undetectable hepatitis C virus (HCV) RNA had reduced liver disease...
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#VisualAbstract: Metformin does not improve survival in patients with high-risk, nonmetastatic breast cancer
Click to read this study in JAMA.
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Cardiac magnetic resonance imaging accurately assessed left ventricular end systolic volume in patients with remodeling due to chronic aortic regurgitation
1. In this retrospective cohort study, the degree of symptom burden correlated well with left...
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Pharmacotherapy is effective for acute insomnia but with worse side effect profiles than placebo
1. Eszopiclone and Lemborexant were more efficacious for acute and long-term insomnia compared to...
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Effectiveness of second dose of COVID-19 vaccines over a 6 month period
1. The effectiveness of COVID-19 vaccines consistently waned over a 26-week period, although...
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Religious and spiritual practices may improve mental health in older adults
1. In the present systematic review and meta-analysis, high religious and spiritual (RS) practices...
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#VisualAbstract: Combination of spartalizumab plus dabrafenib and trametinib does not significantly improve survival in BRAFV600-mutated metastatic melanoma
Click to read this study in the Journal of Clinical Oncology.
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Topical hypericin photodynamic therapy is effective and safe in early-stage T cell lymphoma
1. Hypericin photodynamic therapy was found to be more efficacious in treating early-stage T cell...
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