Oral tacrolimus noninferior to intravenous cyclophosphamide for lupus nephritis
1. Oral tacrolimus was noninferior to intravenous cyclophosphamide for lupus nephritis disease...
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2MM
Comparison of mastectomy and breast reconstruction versus conservative surgery with radiation
1. At 10-year follow-up, patients with early-stage breast cancer who underwent mastectomy with...
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Comprehensive laughter-intervention programs as a means to improve physical and psychological health
1. Amongst a cohort of adults in Japan, a comprehensive laughter-intervention program...
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Early initiation of supplemental parenteral nutrition associated with better outcomes for patients undergoing major abdominal surgery
1. Initiating supplemental parenteral nutrition (PN) at 3 days after major abdominal surgery was...
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Telemedicine bridge clinics may be helpful for opioid use disorder treatment
1. In this study, telemedicine bridge clinics had high show rate and allowed patients to fill...
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Cabozantinib may be a viable first-line treatment in metastatic renal cell collecting duct carcinoma
1. Objective response rate was 35%, with 1 patient showing a complete response and 7 showing a...
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Awake prone positioning may not offer clinical benefits among patients hospitalized with COVID-19-associated hypoxemia
1. In this non-randomized controlled trial including 501 patients with COVID-19-associated...
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Marginalized identities, mistreatment, discrimination, and burnout among US medical students
1. Among a group of US medical students, those with multiple marginalized identities (based on...
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Widespread population immunity of Covid-19 observed in South Africa before Omicron wave
1. Widespread underlying SARS-CoV-2 seropositivity was observed in Gauteng province, South Africa,...
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Prenatal medication for opioid use disorder helps discharge infants back to mothers
1. In this study, medication prescribed for opioid use disorder amongst pregnant women often...
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Ophthalmologic procedures are not associated with increased risk for acute myocardial infarction
1. Based on the study, there was no evidence of increased risk for acute myocardial infarction...
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Vaccination leads to a small absolute risk for shoulder conditions
1. Based on the study, there is a small absolute risk for shoulder conditions after vaccination....
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Baricitinib is superior to placebo for treatment of alopecia areata
1. Oral baricitinib is superior to placebo regarding hair regrowth at 36 weeks. 2. Oral...
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Higher-dose primaquine has higher efficacy in preventing relapse of Plasmodium vivax malaria
1. Compared to lower dose primaquine, higher dose primaquine had higher efficacy in preventing...
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Oral tebipenem pivoxil hydrobromide is effective in treatment of complicated urinary tract infection
1. Compared to intravenous ertapenem, oral tebipenem pivoxil hydrobromide was non-inferior in the...
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Endovascular therapy for large ischemic strokes provides better functional outcomes
1. Compared to medical care alone, treatment of large cerebral infarctions had better functional...
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Rilzabrutinib demonstrates rapid and durable clinical activity for immune thrombocytopenia
1. Rilzabrutinib was active and 400mg twice daily was identified as the dose for further testing...
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Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015
1. Between 1998 to 2015, mortality rates for myocardial infarction, stroke, and pulmonary embolism...
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Adjuvant antipsychotic use in children treated for depression may be associated with movement disorders
1. This cohort study concluded that the concomitant use of antipsychotic and antidepressant...
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