Department of Health Sciences, National Natural Science Foundation of China, Beijing, 100085, PR China; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PR China. Electronic address: sunlichao@cicams.ac.cn.

Institute of Medical Information, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100020, PR China. Electronic address: yang.yuan@imicams.ac.cn.

Institute of Medical Information, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100020, PR China. Electronic address: li.yang@imicams.ac.cn.

State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PR China; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, 230031, Anhui, PR China. Electronic address: liyang@ahmu.edu.cn.

State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PR China; Department of Lung Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin, 300060, PR China. Electronic address: zhangbin_09@tmu.edu.cn.

Department of Health Sciences, National Natural Science Foundation of China, Beijing, 100085, PR China. Electronic address: shirong@nsfc.gov.cn.