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The volume regulated anion channel VRAC regulates NLRP3 inflammasome by modulating itaconate efflux and mitochondria function.

Nov 27, 2023

ABOUT THE EXPERTS

  • Xiaoyan Wu

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

    Xin Yi

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

    Boxin Zhao

    Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou, China.

    Yuanxing Zhi

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

    Ziwei Xu

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

    Ying Cao

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

    Xiong Cao

    Key Laboratory of Mental Health of the Ministry of Education, Key Laboratory of Psychiatric Disorders of Guangdong Province, Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

    Jianxin Pang

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

    Ken Kin Lam Yung

    Department of Science and Environmental Studies, the Education University of Hong Kong, Hong Kong, China.

    Shiqing Zhang

    JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou, China. Electronic address: 13480138@life.hkbu.edu.hk.

    Shuwen Liu

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China. Electronic address: liusw@smu.edu.cn.

    Pingzheng Zhou

    Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China. Electronic address: pzzhou@smu.edu.cn.

REFERENCES & ADDITIONAL READING

PubMed

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