The following is a summary of “Mayer-Rokitansky-Küster-Hauser syndrome patients’ interest, expectations and demands concerning uterus transplantation,” published in the December 2023  issue of Obstetrics and Gynecology by Sousa, et al.

Before beginning a uterine transplantation (UTx) program for women who are suffering from Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH syndrome), it is important to have a deeper understanding of the symptoms suffered by patients and their expectations.

MRKH sufferers were asked to participate in a web-based survey that was carried out via the French National Association network between March and August of 2020. Twenty-eight items in the questionnaire inquired about the respondents’ desire to become parents, the peculiarities of their condition, and any prior reconstructive operations they had undergone, as well as their attitudes and knowledge of UTx.

Of the 148 people who participated in the study, 88% expressed a desire to become parents, and 61% chose UTx as their primary option to achieve this objective. The prospect of having a child and the desire to share the same genetic ancestry were the primary drivers of this decision. After being educated about the typical progression of a UTx regimen, just thirteen percent of the participants reconsidered their decision, and three out of every four decided to go with UT. Uterus transplantation is the first choice for people who are suffering from MRKH conditions to achieve motherhood. It is possible that the creation of UTx programs might satisfy the requirements of this already well-informed demographic.

Source: sciencedirect.com/science/article/abs/pii/S2468784723001411