This commentary review article will instead focus on the recent findings on contraceptive methods in preventing OvCa.

Combined hormonal contraceptive (CHC) use is an effective chemoprevention method for OvCa in the general population and women with genetic disorders.

Salpingectomy, better than tubal ligation, should be offered for ovarian/tubal/peritoneal cancer prevention. Progestogen-only methods can decrease the risk of OvCa via reduced menstrual bleeding and by changes in the hormonal environment that surrounds the ovary.IUDs of any type, through different mechanisms, decrease the risk of OvCa.Barrier methods prevent the passage of germs into the tubes and ovaries and the inflammatory state they produce.

Most contraceptive methods have a mechanism of action that may favor a reduction in the risk of OvCa. The theories of incessant ovulation, retrograde menstruation, and that the fallopian tubes are the site of origin of a proportion of high-grade serous OvCa have led to the recommendation that anovulatory methods, those that decrease menstrual bleeding, and those that blocked tubes, or even better, ‘opportunistic salpingectomy’ are a current approach to prevent OvCa in the population generally and, above all, in the population at risk.

Reference: https://www.tandfonline.com/doi/full/10.1080/13625187.2020.1849617

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